Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1
Travis SM, DAmico K, Yu IM, McMahon C, Hamid S, Ramirez-Arellano G, Jeffrey PD, Hughson FM. Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1. Journal Of Biological Chemistry 2020, 295: 10125-10135. PMID: 32409579, PMCID: PMC7383367, DOI: 10.1074/jbc.ra120.013654.Peer-Reviewed Original ResearchConceptsCoat protein ITarget membraneDsl1 complexSNARE motifEndoplasmic reticulumSNARE complexMembrane-bridging SNARE complexesSensitive factor attachment protein receptorsFactor attachment protein receptorsAttachment protein receptorsN-terminal domainHabc domainMacromolecular machinesCOPI coatVesicle dockingFusion machineryStructural basisMembrane fusionOpen conformationProtein IProtein receptorsDsl1X-ray crystallographySnareCentral hinge