2016
Prenatal stress alters amygdala functional connectivity in preterm neonates
Scheinost D, Kwon SH, Lacadie C, Sze G, Sinha R, Constable RT, Ment LR. Prenatal stress alters amygdala functional connectivity in preterm neonates. NeuroImage Clinical 2016, 12: 381-388. PMID: 27622134, PMCID: PMC5009231, DOI: 10.1016/j.nicl.2016.08.010.Peer-Reviewed Original ResearchConceptsPrenatal stress exposurePreterm neonatesPreterm birthPrenatal stressStress exposureTerm controlsFunctional connectivityAmygdala connectivityNeuropsychiatric disordersResting-state functional magnetic resonance imagingPrenatal stress altersEarly life stressFunctional magnetic resonance imagingMagnetic resonance imagingPeristriate cortexPrenatal exposureHigh riskMaternal stressIndependent cohortNeonatesLeft amygdalaSubcortical regionsResonance imagingAmygdalaCohort
2014
Adaptive mechanisms of developing brain: Cerebral lateralization in the prematurely-born
Kwon SH, Scheinost D, Lacadie C, Sze G, Schneider KC, Dai F, Constable RT, Ment LR. Adaptive mechanisms of developing brain: Cerebral lateralization in the prematurely-born. NeuroImage 2014, 108: 144-150. PMID: 25528658, PMCID: PMC4324328, DOI: 10.1016/j.neuroimage.2014.12.032.Peer-Reviewed Original ResearchConceptsTerm-equivalent agePreterm neonatesPreterm subjectsCerebral lateralizationTerm control subjectsVery preterm subjectsVery preterm neonatesDegree of prematurityImpact of prematurityInter-hemispheric connectivityEquivalent agePreterm birthPreterm infantsThird trimesterControl subjectsBrain injuryLess lateralizationTerm controlsVoxel-based measureFunctional connectivityCortical organizationBA22Interest analysisWernicke's areaYoung adulthoodGABA, Resting-State Connectivity and the Developing Brain
Kwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR. GABA, Resting-State Connectivity and the Developing Brain. Neonatology 2014, 106: 149-155. PMID: 24970028, PMCID: PMC4134402, DOI: 10.1159/000362433.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidTerm-equivalent agePreterm infantsGABA concentrationTerm controlsFunctional connectivityMagnetic resonance imaging (MRI) scansFunctional magnetic resonance imaging (fMRI) scansResting-state functional connectivityRegional GABA concentrationTerm control groupResonance imaging scansResting-state connectivityRight frontal lobeConcentration of GABANAA/cholineMagnetic resonance spectroscopyPreclinical dataImaging scansFrontal lobeControl groupInfantsBrainMRI dataAge