Analytical Approaches to Uncover Genetic Associations for Rare Outcomes: Lessons from West Nile Neuroinvasive Disease
Cahill M, Montgomery R. Analytical Approaches to Uncover Genetic Associations for Rare Outcomes: Lessons from West Nile Neuroinvasive Disease. Methods In Molecular Biology 2022, 2585: 193-203. PMID: 36331775, PMCID: PMC9867870, DOI: 10.1007/978-1-0716-2760-0_17.Peer-Reviewed Original ResearchConceptsWest Nile neuroinvasive diseaseNeuroinvasive diseaseViral infectionWest Nile viral infectionSevere neuroinvasive diseaseMore severe outcomesGenetic factorsRare outcomesLimited cohort sizeSevere West Nile neuroinvasive diseaseWest Nile infectionVector-borne viral infectionSevere outcomesImmune responseSevere diseaseHigh riskFatal diseaseVaccine developmentInfectionDiseaseInfected humansWest NileSerious diseaseOutcomesCohort size