Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
Schultz R, Montgomery R, Belanoff J. Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis. Developmental Biology 1983, 97: 264-273. PMID: 6189752, DOI: 10.1016/0012-1606(83)90085-4.Peer-Reviewed Original ResearchConceptsGerminal vesicle breakdownOocyte cAMPResumption of meiosisOocyte cAMP concentrationMeiotic maturationCumulus cell-oocyte complexesLevels of cAMPCAMP phosphodiesterase inhibitorDbcAMP-containing mediumAntral folliclesPreovulatory antral folliclesPhosphodiesterase inhibitorOocyte meiotic maturationCumulus cellsMouse oocyte meiotic maturationCAMP levelsVesicle breakdownCAMP concentrationDibutyryl cAMPBiochemical changesIBMXPeriod of timePossible roleFolliclesOocytesRegulation of oocyte maturation in the mouse: Possible roles of intercellular communication, cAMP, and testosterone
Schultz R, Montgomery R, Ward-Bailey P, Eppig J. Regulation of oocyte maturation in the mouse: Possible roles of intercellular communication, cAMP, and testosterone. Developmental Biology 1983, 95: 294-304. PMID: 6186544, DOI: 10.1016/0012-1606(83)90030-1.Peer-Reviewed Original ResearchConceptsFollicle-stimulating hormoneCumulus cell-oocyte complexesCumulus cell-enclosed oocytesCholera toxinHeterologous gap junctionsCumulus cellsInhibitory effectCell cAMPCAMP contentMarked increaseCell typesPossible roleGap junctionsIntercellular communicationGroups of oocytesResumption of meiosisCAMP accumulationCAMP generationOocyte cAMPIntracellular cAMPOocyte maturationTestosteroneCAMP levelsCAMP degradationTransient inhibition