2017
Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas
Lazova R, Pornputtapong N, Halaban R, Bosenberg M, Bai Y, Chai H, Krauthammer M. Spitz nevi and Spitzoid melanomas: exome sequencing and comparison with conventional melanocytic nevi and melanomas. Modern Pathology 2017, 30: 640-649. PMID: 28186096, PMCID: PMC5413430, DOI: 10.1038/modpathol.2016.237.Peer-Reviewed Original Research
2016
GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation
Lim YH, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, Narayan D, Genomics Y, McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate KA. GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation. American Journal Of Human Genetics 2016, 99: 443-450. PMID: 27476652, PMCID: PMC4974082, DOI: 10.1016/j.ajhg.2016.06.010.Peer-Reviewed Original ResearchMeSH KeywordsCells, CulturedChild, PreschoolEnzyme ActivationGTP-Binding Protein alpha SubunitsGTP-Binding Protein alpha Subunits, Gq-G11Human Umbilical Vein Endothelial CellsHumansInfantInfant, NewbornIntercellular Signaling Peptides and ProteinsMaleMAP Kinase Signaling SystemMelanocytesMitogen-Activated Protein KinasesMutationProto-Oncogene Proteins c-aktVascular NeoplasmsConceptsLobular capillary hemangiomaVascular tumorsKaposiform hemangioendotheliomaMonths of lifeYears of ageSomatic activating mutationsGNA14 mutationsHuman endothelial cellsPharmacologic interventionsSignificant complicationsCommon neoplasmCapillary hemangiomaInfantile hemangiomasLCH lesionsPrimary human endothelial cellsTherapeutic interventionsActivating mutationsGNA11 mutationsTumorsEndothelial cellsLesionsPotential targetHemangiomaGNA14Somatic mutations
2008
Metastatic Peritoneal Neurocutaneous Melanocytosis
Cajaiba MM, Benjamin D, Halaban R, Reyes-Múgica M. Metastatic Peritoneal Neurocutaneous Melanocytosis. The American Journal Of Surgical Pathology 2008, 32: 156-161. PMID: 18162783, DOI: 10.1097/pas.0b013e3181238cd2.Peer-Reviewed Original ResearchConceptsNeurocutaneous melanocytosisCentral nervous systemComplex cytogenetic rearrangementsSevere neurologic manifestationsVentriculo-peritoneal shuntingPrimary skin melanomaLarge congenital melanocytic neviAtypical cell proliferationCongenital melanocytic neviSpecific diagnostic criteriaRare congenital disorderCNS metastasesNeurologic manifestationsNeurologic symptomsClinical courseLesion variesHistopathologic featuresNeurocutaneous melanosisBiologic featuresMalignant melanomaPeritoneal surfaceAggressive phenotypeDiagnostic criteriaNervous systemProliferation of melanocytes
1986
The involvement of 6p in melanoma
Cowan J, Halaban R, Lane A, Francke U. The involvement of 6p in melanoma. Cancer Genetics 1986, 20: 255-261. PMID: 3943065, DOI: 10.1016/0165-4608(86)90081-6.Peer-Reviewed Original Research