The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells
Halaban R, Lerner A. The dual effect of melanocyte-stimulating hormone (MSH) on the growth of cultured mouse melanoma cells. Experimental Cell Research 1977, 108: 111-117. PMID: 196867, DOI: 10.1016/s0014-4827(77)80016-5.Peer-Reviewed Original ResearchConceptsMelanocyte stimulating hormoneMouse melanoma cellsMelanoma cellsInhibition of growthTyrosinase activityIntracellular levelsRate of proliferationExogenous adenosineLow tyrosinase activityCyclic monophosphateHormoneDual effectHigh tyrosinase activityStimulationCellsActivation of tyrosinaseInhibitionStimulation of growthCulture mediumToxic substances