The multi-faceted potential of CD38 antibody targeting in multiple myeloma
Shallis RM, Terry CM, Lim SH. The multi-faceted potential of CD38 antibody targeting in multiple myeloma. Cancer Immunology, Immunotherapy 2017, 66: 697-703. PMID: 28341874, PMCID: PMC11029060, DOI: 10.1007/s00262-017-1990-2.Peer-Reviewed Original ResearchConceptsCD38 MoAbsEffector mechanismsAutologous stem cell transplantClonal T-cell expansionImmune checkpoint inhibitorsHigh-dose chemotherapyCD38 monoclonal antibodyStem cell transplantMM cell growthT cell expansionAdaptive immune responsesPromising immunotherapeutic agentPivotal clinical studiesPotential tumor antigensMultiple myeloma cellsMM cytotoxicityCheckpoint inhibitorsMM therapyDose chemotherapyMM patientsAntibody therapyCell transplantImmunotherapeutic agentsCD38 antibodyMultiple myeloma