1990
Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity.
Cruz P, Tigelaar R, Bergstresser P. Langerhans cells that migrate to skin after intravenous infusion regulate the induction of contact hypersensitivity. The Journal Of Immunology 1990, 144: 2486-92. PMID: 1969448, DOI: 10.4049/jimmunol.144.7.2486.Peer-Reviewed Original ResearchConceptsLow-dose UVB radiationContact hypersensitivityLangerhans cellsIntravenous infusionLow-dose ultraviolet B (UVB) radiationExposure of LCThy-1UVB radiationSuppressor signalsMesenteric lymph nodesLow-dose UVBEffector signalsSkin graft experimentsLC migrationImmunologic targetsLymph nodesAllogeneic transferCH responsesLymphoid tissueImmune responseSyngeneic miceImmunization modelImmunogenic propertiesInfusionUltraviolet B radiation
1983
Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation.
Elmets C, Bergstresser P, Tigelaar R, Wood P, Streilein J. Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. Journal Of Experimental Medicine 1983, 158: 781-794. PMID: 6193234, PMCID: PMC2187099, DOI: 10.1084/jem.158.3.781.Peer-Reviewed Original ResearchConceptsTolerogenic signalsLow-dose ultraviolet B (UVB) radiationLow-dose ultraviolet radiationAntigen-presenting potentialAntigen-specific unresponsivenessResident Langerhans cellsMechanism of unresponsivenessSuppressor cellsContact hypersensitivityLyt-1Effector stageLangerhans cellsSystemic administrationT cellsLocal applicationUltraviolet B radiationInduction phaseB radiationUnresponsivenessSkinUltraviolet radiationCellsTolerogenDNFBHypersensitivityContact hypersensitivity reactions to dinitrofluorobenzene mediated by monoclonal IgE anti-DNP antibodies.
Ray M, Tharp M, Sullivan T, Tigelaar R. Contact hypersensitivity reactions to dinitrofluorobenzene mediated by monoclonal IgE anti-DNP antibodies. The Journal Of Immunology 1983, 131: 1096-102. PMID: 6193174, DOI: 10.4049/jimmunol.131.3.1096.Peer-Reviewed Original ResearchConceptsContact hypersensitivity reactionHypersensitivity reactionsDNFB challengeUnsensitized controlsAntigen challengeReactive haptenMonoclonal IgE anti-DNP antibodyIgE anti-DNP antibodyIgE anti-hapten antibodyBALB/c miceAllergic contact dermatitis reactionsBiphasic patternIgE-sensitized miceEars of miceCutaneous hypersensitivity reactionsCutaneous hypersensitivity responseCutaneous inflammatory reactionsContact dermatitis reactionsFailure of miceAnti-hapten antibodiesAnti-DNP antibodiesEar challengeEar swellingHypersensitivity responseIgE antibodies