1995
Murine Epidermal Vγ5/Vδ1-T-Cell Receptor+ T Cells Respond to B-Cell Lines and Lipopolysaccharides
Reardon C, Heyborne K, Tsuji M, Zavala F, Tigelaar R, O'Brien R, Born W. Murine Epidermal Vγ5/Vδ1-T-Cell Receptor+ T Cells Respond to B-Cell Lines and Lipopolysaccharides. Journal Of Investigative Dermatology 1995, 105: s58-s61. DOI: 10.1038/jid.1995.12.Peer-Reviewed Original ResearchB cell linesColony-stimulating factorCytokine productionGranulocyte-macrophage colony-stimulating factorTumor necrosis factorT cell clonesB-cell lymphomaAbsence of lipopolysaccharideT cell stimulationMacrophage colony-stimulating factorT Cells RespondCell linesT cell receptorT cell linesIL-10C57BL/6 miceIL-6IL-8B lymphoma cell lineIL-4IL-5IL-2Necrosis factorHuman B lymphoma cell lineBacterial infectionsMurine epidermal V gamma 5/V delta 1-T-cell receptor+ T cells respond to B-cell lines and lipopolysaccharides.
Reardon C, Heyborne K, Tsuji M, Zavala F, Tigelaar R, O'Brien R, Born W. Murine epidermal V gamma 5/V delta 1-T-cell receptor+ T cells respond to B-cell lines and lipopolysaccharides. Journal Of Investigative Dermatology 1995, 105: 58s-61s. PMID: 7615998, DOI: 10.1111/1523-1747.ep12316074.Peer-Reviewed Original ResearchConceptsB cell linesColony-stimulating factorCytokine productionGamma deltaGamma delta T cell linesGranulocyte-macrophage colony-stimulating factorT cell clonesB-cell lymphomaAbsence of lipopolysaccharideT cell stimulationMacrophage colony-stimulating factorCell linesT cell receptorT cell linesIL-10C57BL/6 miceB lymphoma cell lineIL-6IL-8IL-2IL-4IL-5Tumor necrosisT cellsHuman B lymphoma cell line
1988
Thy-1+ epidermal cells in nude mice are distinct from their counterparts in thymus-bearing mice. A study of morphology, function, and T cell receptor expression.
Nixon-Fulton J, Kuziel W, Santerse B, Bergstresser P, Tucker P, Tigelaar R. Thy-1+ epidermal cells in nude mice are distinct from their counterparts in thymus-bearing mice. A study of morphology, function, and T cell receptor expression. The Journal Of Immunology 1988, 141: 1897-903. PMID: 2902136, DOI: 10.4049/jimmunol.141.6.1897.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, SurfaceBlotting, NorthernBlotting, SouthernCell DivisionConcanavalin ADendritic CellsEpidermal CellsEpidermisEthersFemaleInterleukin-2IonomycinMaleMiceMice, Inbred BALB CMice, Inbred CBAMice, NudeReceptors, Antigen, T-CellSpecies SpecificityTetradecanoylphorbol AcetateThy-1 AntigensThymus GlandConceptsIL-2Thy-1Nude miceNormal miceLow-dose IL-2BALB/c miceT cell receptor expressionModest proliferative responseThymus-bearing miceCell receptor expressionT cell differentiationTCR-gamma transcriptsC miceReceptor expressionAthymic miceProliferative responseNormal animalsTCR mRNACalcium ionophoreEpidermal cellsMiceNormal CBACon AFollicular epitheliumPopulation of cellsPhenotypic Heterogeneity and Cytotoxic Activity of Con A and IL-2-Stimulated Cultures of Mouse Thy-1+ Epidermal Cells
Nixon-Fulton J, Hackett J, Bergstresser P, Kumar V, Tigelaar R. Phenotypic Heterogeneity and Cytotoxic Activity of Con A and IL-2-Stimulated Cultures of Mouse Thy-1+ Epidermal Cells. Journal Of Investigative Dermatology 1988, 91: 62-68. PMID: 2898506, DOI: 10.1111/1523-1747.ep12463290.Peer-Reviewed Original ResearchConceptsAntibody-dependent cell-mediated cytotoxicityYAC-1 targetsLyt-2Thy-1Asialo GM1IL-2Con AMouse Thy-1IL-2-stimulated culturesCytotoxic activityDendritic Thy-1NK-sensitive targetsNK-resistant targetsCell-mediated cytotoxicityT-cell markersShort-term cultured cellsPhenotypic heterogeneityMaximum cytotoxic activityYAC-1Interleukin-2Flow cytometryL3T4Population of cellsMouse epidermisLong-term cultureThy-1+ Dendritic Epidermal Cells in Mice: Precursor Frequency Analysis and Cloning of Concanavalin A-Reactive Cells
Takashima A, Nixon-Fulton J, Bergstresser P, Tigelaar R. Thy-1+ Dendritic Epidermal Cells in Mice: Precursor Frequency Analysis and Cloning of Concanavalin A-Reactive Cells. Journal Of Investigative Dermatology 1988, 90: 671-678. PMID: 2896217, DOI: 10.1111/1523-1747.ep12560835.Peer-Reviewed Original ResearchConceptsDendritic epidermal cellsPrecursor frequency analysisIL-2Lyt-2Thy-1Con AGrowth factorExogenous IL-2Higher proliferative responsesFunctional activityCytotoxic activityYAC-1Precursor frequencyProliferative responseMouse Thy-1Dilution microculturesLow cytotoxic activityHigh cytotoxic activityTarget cellsLow responsivenessCells/Vivo activityBulk culturesFiller cellsEpidermal cells
1986
Thy-1+ epidermal cells proliferate in response to concanavalin A and interleukin 2.
Nixon-Fulton J, Bergstresser P, Tigelaar R. Thy-1+ epidermal cells proliferate in response to concanavalin A and interleukin 2. The Journal Of Immunology 1986, 136: 2776-86. PMID: 2870120, DOI: 10.4049/jimmunol.136.8.2776.Peer-Reviewed Original ResearchConceptsPeripheral T cellsIL-2Langerhans cellsRat IL-2T cellsThy-1Con AAnti-T cell reagentsMature peripheral T cellsAKR/J miceComplement depletion studiesT-cell markersConcanavalin AFluorescence-activated cell sorterThy-1 antigenNK cellsMice 20Lyt-1Lyt-2J miceInterleukin-2Maximal responseMouse epidermal cellsAsialo GM1Day 5