1990
Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion.
Gocinski B, Tigelaar R. Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. The Journal Of Immunology 1990, 144: 4121-8. PMID: 1971294, DOI: 10.4049/jimmunol.144.11.4121.Peer-Reviewed Original ResearchConceptsEffector cellsVivo depletionBALB/c miceEffector roleCS effector cellsMonoclonal antibody depletionMurine contact sensitivityDepletion of CD4Depletion of CD8Contact sensitivity responseRole of CD4Activity of CD8Delayed-type hypersensitivityT cell subsetsCutaneous hypersensitivity responseT-cell phenotypeImportant effector roleSubsequent flow cytometric analysisFlow cytometric analysisEnhanced earImmune lymphResidual CD4Adoptive transferSuppressor cellsDistinct CD4
1983
Contact hypersensitivity reactions to dinitrofluorobenzene mediated by monoclonal IgE anti-DNP antibodies.
Ray M, Tharp M, Sullivan T, Tigelaar R. Contact hypersensitivity reactions to dinitrofluorobenzene mediated by monoclonal IgE anti-DNP antibodies. The Journal Of Immunology 1983, 131: 1096-102. PMID: 6193174, DOI: 10.4049/jimmunol.131.3.1096.Peer-Reviewed Original ResearchConceptsContact hypersensitivity reactionHypersensitivity reactionsDNFB challengeUnsensitized controlsAntigen challengeReactive haptenMonoclonal IgE anti-DNP antibodyIgE anti-DNP antibodyIgE anti-hapten antibodyBALB/c miceAllergic contact dermatitis reactionsBiphasic patternIgE-sensitized miceEars of miceCutaneous hypersensitivity reactionsCutaneous hypersensitivity responseCutaneous inflammatory reactionsContact dermatitis reactionsFailure of miceAnti-hapten antibodiesAnti-DNP antibodiesEar challengeEar swellingHypersensitivity responseIgE antibodies