2009
Skin immune surveillance by T cells—A new order?
Strid J, Tigelaar RE, Hayday AC. Skin immune surveillance by T cells—A new order? Seminars In Immunology 2009, 21: 110-120. PMID: 19369094, DOI: 10.1016/j.smim.2009.03.002.Peer-Reviewed Original ResearchConceptsImmune surveillanceAdaptive immune surveillanceStress-induced antigensSystemic immune cellsSkin immune surveillanceLocal lymphocytesOrgan dysfunctionDendritic cellsImmune cellsT cellsEpithelial cellsTissue integrityCellsSurveillanceBody surfaceImmunopathologyImmunoregulationDysfunctionLymphocytesInfectionAntigenImmunoprotectionStress response
1993
THE TREATMENT OF MASTOCYTOMA CELLS WITH 8‐METHOXYPSORALEN AND LONG‐WAVELENGTH ULTRAVIOLET RADIATION ENHANCES CELLULAR IMMUNOGENICITY: PRELIMINARY RESULTS
Gasparro F, Malane M, Maxwell V, Tigelaar R. THE TREATMENT OF MASTOCYTOMA CELLS WITH 8‐METHOXYPSORALEN AND LONG‐WAVELENGTH ULTRAVIOLET RADIATION ENHANCES CELLULAR IMMUNOGENICITY: PRELIMINARY RESULTS. Photochemistry And Photobiology 1993, 58: 682-688. PMID: 8284324, DOI: 10.1111/j.1751-1097.1993.tb04952.x.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaLong-wavelength ultraviolet radiationT-cell lymphomaMurine immune systemP1 cellsNew surface antigensCellular immunogenicityImmunized miceUVA photochemotherapyImmunosuppressed miceImmune cellsDBA/2 miceCell lymphomaSurface antigenImmune systemSignificant protectionPilot studyMiceImmunogenicityMastocytoma cellsN-methyl-N'UVA treatmentUltraviolet radiationTreatmentAntigen
1992
Expression of mouse Tla region class I genes in tissue enriched for γδ cells
Eghtesady P, Brorson K, Cheroutre H, Tigelaar R, Hood L, Kronenberg M. Expression of mouse Tla region class I genes in tissue enriched for γδ cells. Immunogenetics 1992, 36: 377-388. PMID: 1388139, DOI: 10.1007/bf00218045.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalBase SequenceBlotting, NorthernDNA ProbesFetusGene ExpressionGenes, MHC Class IMiceMice, Inbred BALB CMice, Inbred C57BLMolecular Sequence DataMultigene FamilyPolymerase Chain ReactionReceptors, Antigen, T-Cell, gamma-deltaRepetitive Sequences, Nucleic AcidT-LymphocytesConceptsΓδ T cellsT cellsPolymerase chain reactionTla region genesClass IΓδ T lymphocytesPresentation of antigensThymus leukemia antigenMajor histocompatibility complexRegion gene productsΓδ cellsLeukemia antigenAntigen presentationT lymphocytesRegion genesFetal tissuesTL antigensMouse major histocompatibility complexMonoclonal antibodiesHistocompatibility complexPattern of expressionAntigenChain reactionRecent evidenceNorthern blot analysis
1983
Thy-1 Antigen-Bearing Dendritic Cells Populate Murine Epidermis
Bergstresser P, Tigelaar R, Dees J, Streilein J. Thy-1 Antigen-Bearing Dendritic Cells Populate Murine Epidermis. Journal Of Investigative Dermatology 1983, 81: 286-288. PMID: 6136547, DOI: 10.1111/1523-1747.ep12518332.Peer-Reviewed Original ResearchConceptsLangerhans cellsMurine epidermisCutaneous T-cell lymphomaEar epidermisDendritic cell populationsStrain BALB/cT-cell lymphomaEpidermal Langerhans cellsThy-1.2 antigenBALB/cCell populationsThy-1 antigenT lymphocytesIa antigensDistinct cell populationsMalignant counterpartsThy-1Monoclonal antibodiesStrain B10.AAntigenMelanocytesImmunofluorescence microscopySkin surfaceEpidermisMature melanocytesSALT: Skin-Associated Lymphoid Tissues
Streilein J, Tigelaar R. SALT: Skin-Associated Lymphoid Tissues. 1983, 95-130. DOI: 10.1007/978-1-4613-3670-9_6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSkin-associated lymphoid tissueImmune responseExogenous antigensLymphoid tissueImmune systemUnique immune responseSpecific immune responseMucous membrane surfacesImmunologic apparatusLymph nodesEffector cellsImmunocompetent lymphocytesRespiratory tractEffector mechanismsImmunologic influenceOral routeNervous systemOrgan systemsAntigenPathogenic potentialSpecific tissuesTissueUnrelated tissuesGutCells
1976
Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells
Janeway C, Mosier D, Tigelaar R. Specific loss of stimulator activity following mixed lymphocyte reactions is due to cytotoxic cells. European Journal Of Immunology 1976, 6: 747-750. PMID: 138373, DOI: 10.1002/eji.1830061017.Peer-Reviewed Original ResearchConceptsMixed lymphocyte reactionFresh spleen cellsSpleen cellsLymphocyte reactionOne-way mixed-lymphocyte reactionPrimary mixed lymphocyte reactionMouse strainsStimulator activityCytotoxic T cellsStrong mixed lymphocyte reactionsUnrelated mouse strainsCongenic mouse strainsCytotoxic cellsStimulator cellsT cellsRelease assaysSpecific lossCell activityResidual cellsB subregionRestricted expressionLymphocytesSuch cellsAntigenCells