Capsaicin-sensitive primary sensory neurons are potent modulators of murine delayed-type hypersensitivity reactions.
Girolomoni G, Tigelaar R. Capsaicin-sensitive primary sensory neurons are potent modulators of murine delayed-type hypersensitivity reactions. The Journal Of Immunology 1990, 145: 1105-12. PMID: 2380551, DOI: 10.4049/jimmunol.145.4.1105.Peer-Reviewed Original ResearchConceptsDelayed-type hypersensitivity reactionPrimary sensory neuronsHypersensitivity reactionsSensory neuronsCapsaicin-sensitive primary sensory neuronsBALB/c miceCapsaicin-pretreated miceEffector T cellsContact sensitivity reactionAdoptive transfer experimentsCutaneous inflammatory reactionsTopical capsaicinCapsaicin pretreatmentNeurogenic inflammationC miceNeuropeptide releaseHistologic studyInflammatory reactionT cellsPeptidergic neuronsIrritant reactionsSensitivity reactionsSuch neuronsCapsaicinPotent modulator