2009
Baseline brain energy supports the state of consciousness
Shulman RG, Hyder F, Rothman DL. Baseline brain energy supports the state of consciousness. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 11096-11101. PMID: 19549837, PMCID: PMC2708743, DOI: 10.1073/pnas.0903941106.Peer-Reviewed Original ResearchConceptsLoss of consciousnessBrain energyConscious stateHigh-frequency neuronal activityCerebral energy consumptionBrain energy consumptionCerebral energyEnsembles of neuronsRat brainSomatosensory responsesNeuronal activityGamma-band rangeNeuronal propertiesFiring rateSensory stimulationNeuronal signalingPET measurementsAnesthesiaFMRI patternsFMRI activity patternsOxygen consumptionState of consciousnessStimulationBehavioral abilitiesMagnetic resonance spectroscopy
2008
Neurophysiology of functional imaging
van Eijsden P, Hyder F, Rothman DL, Shulman RG. Neurophysiology of functional imaging. NeuroImage 2008, 45: 1047-1054. PMID: 18801442, PMCID: PMC2677905, DOI: 10.1016/j.neuroimage.2008.08.026.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainBrain MappingCognitionEvoked PotentialsHumansMagnetic Resonance ImagingModels, NeurologicalNeurophysiologyPositron-Emission TomographyConceptsCognitive psychologyCognitive modularityPsychological conceptsPsychological propertiesCognitive conceptsObjective physical measuresMental lifeMental functionsBrain energyBOLD signalSeparable areasSubjective conceptFMRIDegree of awarenessFunctional imagingEmpirical responsesPsychologySensory functionPhysical measuresStimuliNeurophysiologyBrainAdjectivesOperational termsRevolutionary hopes
2007
Energetics of neuronal signaling and fMRI activity
Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F. Energetics of neuronal signaling and fMRI activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 20546-20551. PMID: 18079290, PMCID: PMC2154468, DOI: 10.1073/pnas.0709515104.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsElectric StimulationMagnetic Resonance ImagingMaleNeural ConductionNeurons, AfferentRatsRats, Sprague-DawleySignal TransductionSomatosensory CortexConceptsRSN activityContralateral S1FMRI activationBaseline stateContralateral primary somatosensory cortexPrimary somatosensory cortexSomatosensory cortexIntracortical interactionsFiring rateNeuronal signalingFMRI activityEnsemble activityEnsemble firingStimulationHalothaneCortexNeuronsBaselineActivationFMRI dataLarge majorityAnesthesiaActivityRatsA BOLD search for baseline
Shulman RG, Rothman DL, Hyder F. A BOLD search for baseline. NeuroImage 2007, 36: 277-281. PMID: 17223362, PMCID: PMC2684871, DOI: 10.1016/j.neuroimage.2006.11.035.Peer-Reviewed Original Research