2024
Generalized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning
Macdonald-Gagnon G, Stefanovics E, Potenza M, Pietrzak R. Generalized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning. Journal Of Psychiatric Research 2024, 171: 263-270. PMID: 38325107, DOI: 10.1016/j.jpsychires.2024.02.013.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderMild anxiety symptomsAnxiety symptomsMilitary veteransU.S. veteransCorrelates of generalized anxiety disorderCorrelates of anxiety symptomsAnxiety symptom severityU.S. military veteransAnxiety disordersGeneralized anxietyPoor mental healthSuicidal thoughtsSymptom severityMental disordersExcessive anxietyAnxietyMagnitude associationsMental healthFunctional impairmentVeteransFunctional correlatesClinical samplesNationally representative sampleSymptomsFunctional correlates of a novel 8-factor model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Stiltner B, Fischer I, Duek O, Polimanti R, Harpaz-Rotem I, Pietrzak R. Functional correlates of a novel 8-factor model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Psychiatric Research 2024, 171: 69-74. PMID: 38244335, DOI: 10.1016/j.jpsychires.2024.01.017.Peer-Reviewed Original ResearchConceptsModels of posttraumatic stress disorderPosttraumatic stress disorderNational Health and ResilienceU.S. military veteransArousal symptomsSuicidal ideationVeterans StudyCurrent depressionSymptom clustersMilitary veteransPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder symptomsPosttraumatic Stress Disorder ChecklistAnxious arousal symptomsDysphoric arousal symptomsIntrusive symptom clustersOdds of suicidal ideationFunctional correlatesMulti-faceted disorderExternalizing behavioral symptomsAssociated with lower oddsAssociated with higher oddsSymptom structureAvoidance symptomsDSM-5
2023
Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort
Beaudoin F, An X, Basu A, Ji Y, Liu M, Kessler R, Doughtery R, Zeng D, Bollen K, House S, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Murty V, McGrath M, Hudak L, Pascual J, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Neil B, Sergot P, Sanchez L, Bruce S, Baker J, Joormann J, Miller M, Pietrzak R, Barch D, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, Koenen K, Ressler K, McLean S. Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort. Translational Psychiatry 2023, 13: 4. PMID: 36609484, PMCID: PMC9823011, DOI: 10.1038/s41398-022-02289-y.Peer-Reviewed Original Research
2022
Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma
Harnett N, Dumornay N, Delity M, Sanchez L, Mohiuddin K, Musey P, Seamon M, McLean S, Kessler R, Koenen K, Beaudoin F, Lebois L, van Rooij S, Sampson N, Michopoulos V, Maples-Keller J, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, McGrath M, Hudak L, Pascual J, House S, An X, Stevens J, Neylan T, Jovanovic T, Linnstaedt S, Germine L, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Smoller J, Luna B, Harte S, Elliott J, Ressler K. Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma. Psychological Medicine 2022, 53: 2553-2562. PMID: 35094717, PMCID: PMC9339026, DOI: 10.1017/s0033291721004475.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPrevious trauma exposureTrauma exposurePosttraumatic depressionPrior differencesChildhood emotional abusePrior trauma exposureSelf-report assessmentsWhite participantsPosttraumatic stressStress disorderAnxiety symptomsEmotional abuseLife stressorsPTSD ratesEarly aftermathPosttraumatic dysfunctionAnxietySymptom trajectoriesRecent traumaEthnic differencesAURORA studyParticipantsSymptom recoveryRecent research
2015
Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study
Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Restrepo C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P. Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study. JAMA Psychiatry 2015, 72: 284-291. PMID: 25629787, DOI: 10.1001/jamapsychiatry.2014.2476.Peer-Reviewed Original ResearchConceptsPreclinical Alzheimer's diseaseSubjective memory complaintsElevated anxiety symptomsVerbal memoryExecutive functionGlobal cognitionAnxiety symptomsCognitive declineCognitive changesMemory complaintsAβ statusDepressive symptomsLow anxiety groupComprehensive neuropsychological evaluationHigh anxiety groupRole of anxietyFlorbetapir F 18Visual memoryCognitive domainsVisuospatial abilitiesMild cognitive impairmentNeuropsychological evaluationCognitive functionProspective cohort studyMore rapid decline