Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: An ACTTION study
Farrar JT, Troxel AB, Haynes K, Gilron I, Kerns RD, Katz NP, Rappaport BA, Rowbotham MC, Tierney AM, Turk DC, Dworkin RH. Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: An ACTTION study. Pain 2014, 155: 1622-1631. PMID: 24831421, DOI: 10.1016/j.pain.2014.05.009.Peer-Reviewed Original ResearchConceptsDiabetic peripheral neuropathyLikelihood of responseClinical trialsPostherpetic neuralgiaPainful diabetic peripheral neuropathyAddiction Clinical Trial TranslationsNetworks (ACTTION) public-private partnershipBaseline pain levelsPlacebo-treated groupRandomized clinical trialsAnalgesic clinical trialsPatient-level dataClinical trial dataExploratory logistic regressionAvailable baseline factorsNeuropathic painPain diaryPain levelsBaseline factorsPain therapyPeripheral neuropathyPatient sexPatients' baselinePain ratingsStudy protocol