Higher prevalence of kidney function impairment among older people living with HIV in Uganda
Ssemasaazi A, Kalyesubula R, Manabe Y, Mbabazi P, Naikooba S, Ssekindi F, Nasuuna E, Byakika-Kibwika P, Castelnuovo B. Higher prevalence of kidney function impairment among older people living with HIV in Uganda. BMC Nephrology 2024, 25: 321. PMID: 39334034, PMCID: PMC11428404, DOI: 10.1186/s12882-024-03761-1.Peer-Reviewed Original ResearchConceptsKidney function impairmentChronic kidney diseaseAntiretroviral therapyOlder PLWHFunctional impairmentKidney functionKidney diseaseHIV-related inflammationProgression of kidney diseasePrevalence of proteinuriaMultivariate logistic regression modelBurden of chronic kidney diseaseMeasures of kidney functionDiagnosis of hypertensionCross-sectional studyConclusionsHIV infectionHIV-related clinical characteristicsClinical characteristicsInstitution of measuresLogistic regression modelsDiabetes mellitusFemale sexHIVProteinuriaPLWHHealth-related quality of life and hypertension in people with HIV on long-term antiretroviral therapy in Uganda
Batte C, Semulimi A, Mukisa J, Nakabuye M, Nidoi J, Mukunya D, Ratanshi R, Castelnuovo B, Lamorde M, Meya D, Checkley W, Kalyesubula R, Siddharthan T, Babigumira J. Health-related quality of life and hypertension in people with HIV on long-term antiretroviral therapy in Uganda. PLOS ONE 2024, 19: e0306928. PMID: 39116145, PMCID: PMC11309503, DOI: 10.1371/journal.pone.0306928.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeHealth-related qualityQuality of lifeHRQoL scoresLong-term antiretroviral therapyAssociated with lower HRQoL scoresMedian health utility scorePhysical health scoresAntiretroviral therapyLower HRQOL scoresHealth utility scoresMedical Outcomes StudyEQ-5D-5LQuality-of-life assessmentManagement of PWHScores of peopleHealth scoresCompare HRQoLPlan early interventionsHRQoL dataHistory of smokingUrban clinicEQ-5DHRQoLUtility scores