2009
Spatial distribution of intracranially recorded spikes in medial and lateral temporal epilepsies
Goncharova II, Zaveri HP, Duckrow RB, Novotny EJ, Spencer SS. Spatial distribution of intracranially recorded spikes in medial and lateral temporal epilepsies. Epilepsia 2009, 50: 2575-2585. PMID: 19674048, DOI: 10.1111/j.1528-1167.2009.02258.x.Peer-Reviewed Original ResearchConceptsMedial temporal structuresInterictal spikesLT patientsCortical areasNeocortical seizure onsetsSleep-related increaseSpike rateLateral temporal epilepsyExtratemporal areasTemporal epilepsySeizure onsetIntracranial monitoringLT groupMT groupPatientsFrontal spikesSeizuresGreater numberSleepGroupTemporal structureEpilepsySpikes
2008
Temporal distributions of seizure occurrence from various epileptogenic regions
Durazzo TS, Spencer SS, Duckrow RB, Novotny EJ, Spencer DD, Zaveri HP. Temporal distributions of seizure occurrence from various epileptogenic regions. Neurology 2008, 70: 1265-1271. PMID: 18391158, DOI: 10.1212/01.wnl.0000308938.84918.3f.Peer-Reviewed Original ResearchConceptsMesial temporal lobeSeizure occurrencePartial epilepsyTemporal lobeBrain regionsParietal seizuresSeizure distributionNeocortical temporal lobeParietal lobe seizuresTemporal lobe seizuresFrontal lobe seizuresConsecutive adult subjectsCortical brain regionsCircadian rhythmNeocortical temporalSurgical resectionTemporal seizuresIntracranial EEG recordingsEpileptogenic regionSeizuresAdult subjectsEpilepsyEndogenous circadian rhythmLobeEEG recordings
2007
Daily Variation in an Intracranial EEG Feature in Humans Detected by a Responsive Neurostimulator System
Duckrow RB, Tcheng TK. Daily Variation in an Intracranial EEG Feature in Humans Detected by a Responsive Neurostimulator System. Epilepsia 2007, 48: 1614-1620. PMID: 17442001, DOI: 10.1111/j.1528-1167.2007.01091.x.Peer-Reviewed Original Research
2005
Normal magnetic resonance imaging and medial temporal lobe epilepsy: the clinical syndrome of paradoxical temporal lobe epilepsy.
Cohen-Gadol AA, Bradley CC, Williamson A, Kim JH, Westerveld M, Duckrow RB, Spencer DD. Normal magnetic resonance imaging and medial temporal lobe epilepsy: the clinical syndrome of paradoxical temporal lobe epilepsy. Journal Of Neurosurgery 2005, 102: 902-9. PMID: 15926717, DOI: 10.3171/jns.2005.102.5.0902.Peer-Reviewed Original ResearchConceptsMedial temporal lobe epilepsyMedial temporal sclerosisTemporal lobe epilepsyAnteromedial temporal resectionPTLE groupDentate granule cellsLobe epilepsyMTS groupTemporal resectionClinical featuresNeuron lossSeizure historyHippocampal slicesGranule cellsNormal magnetic resonance imagingBlinded visual inspectionPyramidal cell lossDistinct clinical featuresHippocampal cell densityT2 signal changeSignificant neuron lossHippocampal volumetric measurementsMagnetic resonance imagingVolumetric measurementsSharp electrode recordings
2001
Distinguishing Subtypes of Temporal Lobe Epilepsy with Background Hippocampal Activity
Zaveri H, Duckrow R, De Lanerolle N, Spencer S. Distinguishing Subtypes of Temporal Lobe Epilepsy with Background Hippocampal Activity. Epilepsia 2001, 42: 725-730. PMID: 11422326, DOI: 10.1046/j.1528-1157.2001.00500.x.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisTemporal lobe epilepsyLobe epilepsySurgical outcomesIntractable temporal lobe epilepsyPoor surgical outcomesGood surgical outcomeMedial temporal structuresMedial temporal lobeDelta band powerTemporal sclerosisRetrospective studyHippocampal tissueBackground EEGSeizure onsetIndividual patientsSurgical proceduresIntracranial monitoringTemporal lobeGamma frequency bandClinical observationsPatientsAnterior hippocampusCell lossSubtypes
1992
Regional coherence and the transfer of ictal activity during seizure onset in the medial temporal lobe
Duckrow R, Spencer S. Regional coherence and the transfer of ictal activity during seizure onset in the medial temporal lobe. Clinical Neurophysiology 1992, 82: 415-422. PMID: 1375548, DOI: 10.1016/0013-4694(92)90046-k.Peer-Reviewed Original ResearchConceptsMedial temporal lobeSeizure onsetTemporal lobeBrain regionsSustained seizure activityHippocampal depth electrodesHuman medial temporal lobeConsecutive patientsResective surgerySeizure dischargesSeizure activityEpileptiform activityIctal activityPosterior hippocampusDepth electrodesNeuronal entrainmentTransient increaseIctal periodNeuronal synchronizationPossible resective surgeryEEG activityOnsetLobeAdjacent contactsSec epochs