2001
Functional overlap of IP3- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons
Turner D, Segura B, Cowles R, Zhang W, Mulholland M. Functional overlap of IP3- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons. AJP Gastrointestinal And Liver Physiology 2001, 281: g208-g215. PMID: 11408274, DOI: 10.1152/ajpgi.2001.281.1.g208.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine Diphosphate RiboseAdenosine TriphosphateAnesthetics, LocalAnimalsBiological TransportCaffeineCalciumCalcium Channel BlockersCinnarizineCyclic ADP-RiboseDantroleneGuinea PigsInositol 1,4,5-TrisphosphateMicroinjectionsMuscle Relaxants, CentralMyenteric PlexusNeuronsPhosphodiesterase InhibitorsProcaineRyanodineConceptsMyenteric neuronsReceptor subtypesGuinea pig myenteric neuronsDifferent receptor subtypesMobilization of intracellularSuperfusion techniqueCalcium storesRyR antagonistSubsequent perfusionATP exposureNeuronsRyanodine receptorCADP-riboseAntagonistIntracellular microinjectionPerfusionMicroM ATPSubtypesRyRsIntracellularReceptorsTrisphosphate receptorCinnarizineSpecific ligandsMicroinjection
2000
Cholinergic intrapancreatic neurons induce Ca2+ signaling and early-response gene expression in pancreatic acinar cells
Turner D, Cowles R, Segura B, Romanchuk G, Barnhart D, Mulholland M. Cholinergic intrapancreatic neurons induce Ca2+ signaling and early-response gene expression in pancreatic acinar cells. Journal Of Gastrointestinal Surgery 2000, 4: 475-480. PMID: 11077322, DOI: 10.1016/s1091-255x(00)80089-x.Peer-Reviewed Original ResearchConceptsPancreatic acinar cellsC-fos expressionIntrapancreatic neuronsAcinar cellsEarly response gene expressionPancreatic exocrine functionIntracellular calcium levelsC-Fos proteinAR42J pancreatic acinar cellsExocrine functionCholinergic stimulationNeuronal depolarizationIntracellular calciumLong-term consequencesCalcium levelsNeuronal regulationNeuronsGene expressionPancreatic lobulesCalcium signalingCellsDepolarizationExpressionAverage increaseAgonists