Phenobarbital Monotherapy for the Management of Alcohol Withdrawal Syndrome in Surgical-Trauma Patients
Ammar MA, Ammar AA, Rosen J, Kassab HS, Becher RD. Phenobarbital Monotherapy for the Management of Alcohol Withdrawal Syndrome in Surgical-Trauma Patients. Annals Of Pharmacotherapy 2020, 55: 294-302. PMID: 32830517, DOI: 10.1177/1060028020949137.Peer-Reviewed Original ResearchMeSH KeywordsBenzodiazepinesFemaleHumansHypnotics and SedativesMalePhenobarbitalRetrospective StudiesSubstance Withdrawal SyndromeWounds and InjuriesConceptsManagement of AWSAlcohol withdrawal syndromePhenobarbital monotherapyRespiratory depressionWithdrawal syndromeDevelopment of AWSSurgical trauma intensive care unitPatient experienced hypotensionSurgical trauma patientsInvasive mechanical ventilationSafety end pointFirst-line therapyMajority of patientsManagement of patientsIntensive care unitExperienced hypotensionTaper regimenSignificant hypotensionAdjunct therapyIll patientsLoading doseCare unitMechanical ventilationPatient populationSurgical trauma