2005
Molecular Biology of Renal Acid–Base Transporters
Moe O, Baum M, Alpern R. Molecular Biology of Renal Acid–Base Transporters. 2005, 141-198. DOI: 10.1201/b14402-9.Peer-Reviewed Original ResearchAcid-base transportersProtein of interestClassical protein chemistryRecombinant DNA techniquesFunctional complementationMammalian cellsRegulatory proteinsRegulatory mechanismsWhole organismIndividual transportersMembrane vesiclesDNA techniquesMolecular biologyHigh abundanceProtein chemistryXenopus oocytesMolecular definitionTransportersProteinCurrent knowledgeCell culturesIndividual nephron segmentsAcid-base balanceComplementationCloning
2004
OKP cells express the Na-dicarboxylate cotransporter NaDC-1
Aruga S, Pajor AM, Nakamura K, Liu L, Moe OW, Preisig PA, Alpern RJ. OKP cells express the Na-dicarboxylate cotransporter NaDC-1. American Journal Of Physiology - Cell Physiology 2004, 287: c64-c72. PMID: 14973148, DOI: 10.1152/ajpcell.00061.2003.Peer-Reviewed Original ResearchConceptsCitrate reabsorptionOKP cellsProximal tubulesDependent citrate uptakeOpossum kidney cell lineUrinary citrate concentrationChronic metabolic acidosisRate of reabsorptionRenal proximal tubulesMetabolic acidosisStone formationKidney stonesKidney cell lineCotransporter 1ReabsorptionCell linesCitrate transportMRNA abundanceXenopus oocytesAcid regulationTubulesNaDC-1Citrate uptakeSuccinate transportHypocitraturia