2005
Molecular Biology of Renal Acid–Base Transporters
Moe O, Baum M, Alpern R. Molecular Biology of Renal Acid–Base Transporters. 2005, 141-198. DOI: 10.1201/b14402-9.Peer-Reviewed Original ResearchAcid-base transportersProtein of interestClassical protein chemistryRecombinant DNA techniquesFunctional complementationMammalian cellsRegulatory proteinsRegulatory mechanismsWhole organismIndividual transportersMembrane vesiclesDNA techniquesMolecular biologyHigh abundanceProtein chemistryXenopus oocytesMolecular definitionTransportersProteinCurrent knowledgeCell culturesIndividual nephron segmentsAcid-base balanceComplementationCloning
1997
Adaptation to low-K+ media increases H(+)-K(+)-ATPase but not H(+)-ATPase-mediated pHi recovery in OMCD1 cells
Guntupalli J, Onuigbo M, Wall S, Alpern RJ, DuBose TD. Adaptation to low-K+ media increases H(+)-K(+)-ATPase but not H(+)-ATPase-mediated pHi recovery in OMCD1 cells. American Journal Of Physiology 1997, 273: c558-c571. PMID: 9277353, DOI: 10.1152/ajpcell.1997.273.2.c558.Peer-Reviewed Original Research
1995
Molecular cloning of ion transporters: potential clinical implications.
Cano A, Alpern R. Molecular cloning of ion transporters: potential clinical implications. Seminars In Nephrology 1995, 15: 2-8. PMID: 7754253.Peer-Reviewed Original ResearchConceptsIon transportersIntegral membrane proteinsStructure/functionUnderstanding of functionMembrane proteinsMolecular cloningTransporter proteinsHereditary ovalocytosisProteinHyperkalemic periodic paralysisCloningGenetic disordersTransportersMyotonia congenitaMultiple levelsAbnormal structurePotential clinical implicationsPeriodic paralysisEnzymeHereditary spherocytosisRegulationOvalocytosisCystic fibrosisFunction