2019
Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease
Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R. Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease. Kidney International 2019, 95: 797-814. PMID: 30904067, PMCID: PMC6543531, DOI: 10.1016/j.kint.2018.11.042.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseKidney diseaseKidney injuryCisplatin-induced chronic kidney diseaseCisplatin-induced acute kidney injuryToll-like receptor 2Regulated necrosis pathwaysReversible kidney injuryAcute kidney injuryChronic kidney injuryProximal tubular damageKidney injury markersDoses of cisplatinEvidence of fibrosisMechanisms of progressionEffective chemotherapeutic agentWestern blot analysisFirst doseInjury markersIntraperitoneal cisplatinSignificant nephrotoxicityTubular damageKidney functionSecond doseCisplatin administration
2011
Colonic in situ mantle cell lymphoma
Neto AG, Oroszi G, Protiva P, Rose M, Shafi N, Torres R. Colonic in situ mantle cell lymphoma. Annals Of Diagnostic Pathology 2011, 16: 508-514. PMID: 21840231, DOI: 10.1016/j.anndiagpath.2011.05.001.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorBiopsyCarcinoma in SituChromosomes, Human, Pair 11Chromosomes, Human, Pair 14Colonic NeoplasmsColonoscopyCyclin D1Disease ProgressionHumansIn Situ Hybridization, FluorescenceIntestinal MucosaLymph NodesLymphoma, Mantle-CellMaleMiddle AgedRetrospective StudiesTranslocation, GeneticConceptsMantle cell lymphomaSitu mantle cell lymphomaColonic biopsiesLymphoid aggregatesCell lymphomaCyclin D1-positive cellsPrimary GI lymphomaSmall lymphoid aggregatesBenign colonic mucosaGI lymphomaSitu lymphomaUnderwent colonoscopyLymph nodesRandom biopsiesIleocolic intussusceptionColonic mucosaGastrointestinal tractPositive cellsBiopsyLymphomaPleomorphic morphologyCyclin D1Situ hybridization analysisFirst caseSecond presentation