2024
Macrophage Migration Inhibitory Factor as a Therapeutic Target in Neuro-Oncology: A Review
Jarmula J, Lee J, Lauko A, Rajappa P, Grabowski M, Dhawan A, Chen P, Bucala R, Vogelbaum M, Lathia J. Macrophage Migration Inhibitory Factor as a Therapeutic Target in Neuro-Oncology: A Review. Neuro-Oncology Advances 2024, vdae142. DOI: 10.1093/noajnl/vdae142.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorPrimary CNS tumorsCentral nervous systemMigration inhibitory factorCNS tumorsPrimary central nervous systemInhibitory factorTherapeutic targetPre-clinical studiesFunctions of macrophage migration inhibitory factorPreclinical modelsImmune evasionSmall molecule inhibitorsNeuro-oncologyClinical trialsTumor initiationClinical translationMonoclonal antibodiesTumorigenic processNervous systemTherapeutic requirementsCell proliferationTherapeutic developmentTumorEffective target
2000
Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF)
Mitchell R, Bucala R. Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF). Seminars In Cancer Biology 2000, 10: 359-366. PMID: 11100884, DOI: 10.1006/scbi.2000.0328.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorMigration inhibitory factorInhibitory factorPotent pro-inflammatory cytokinePro-inflammatory cytokinesInflammatory responseTumor progressionTumor angiogenesisTumor suppressor activitySuppressor activityCell proliferationRecent studiesGrowth-promoting propertiesCytokinesNeoplasiaMultiple aspectsProgression