Diminished vaginal HOXA13 expression in women with pelvic organ prolapse
Connell KA, Guess MK, Tate A, Andikyan V, Bercik R, Taylor HS. Diminished vaginal HOXA13 expression in women with pelvic organ prolapse. Menopause The Journal Of The North American Menopause Society 2009, 16: 529-533. PMID: 19423998, PMCID: PMC2704499, DOI: 10.1097/gme.0b013e31818fb0c2.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesFemaleHomeodomain ProteinsHumansMiddle AgedUterine ProlapseVaginaConceptsPelvic organ prolapsePremenopausal controlsPremenopausal womenOrgan prolapseHOXA13 expressionPOP groupExpression of HOXA13Real-time polymerase chain reactionExtracellular matrix metabolismEstrogen therapyPostmenopausal womenYounger patientsLeuprolide groupSmoking cessationLeuprolide acetatePolymerase chain reactionBiopsy specimensPreventive strategiesGenetic predispositionVaginal expressionProlapseMatrix metabolismWeight lossWomenVagina