Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes
Sinha R, Fox HC, Hong KI, Hansen J, Tuit K, Kreek MJ. Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes. JAMA Psychiatry 2011, 68: 942-952. PMID: 21536969, PMCID: PMC3668981, DOI: 10.1001/archgenpsychiatry.2011.49.Peer-Reviewed Original ResearchConceptsAlcohol-dependent patientsAlcohol relapseCue-induced alcohol cravingTreatment outcomesAdrenal sensitivityAlcohol cravingCommunity mental health centerCue-induced anxietyEarly alcohol recoveryHPA axis dysregulationHPA axis functionHPA axis responseMental health centersCue-induced alcoholAlcohol cuesStress-induced alcoholHospital-based research unitAlcohol-dependent individualsCue-Induced CravingCorticotropin levelsAxis dysregulationAxis functionAdrenal axisRelapse riskHealthy controls