2023
Chronic pain, chronic stress and substance use: overlapping mechanisms and implications
Schaffer J, Fogelman N, Seo D, Sinha R. Chronic pain, chronic stress and substance use: overlapping mechanisms and implications. Frontiers In Pain Research 2023, 4: 1145934. PMID: 37415830, PMCID: PMC10320206, DOI: 10.3389/fpain.2023.1145934.Peer-Reviewed Original ResearchChronic painChronic stressSubstance useSubstance misuseCommon reasons adultsCommon pathophysiologic processChronic pain pathologiesMedial prefrontal circuitsPrefrontal cortex dysfunctionPrescription opioidsPain pathologiesPathophysiologic processesPainBrain areasBiologic underpinningsMedical careReasons adultsEnormous burdenNeural circuitryPrefrontal circuitsVentromedial prefrontal cortex dysfunctionPsychobiological processesIndividual wellnessWellnessRisk
2022
Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease
Cherry J, Kamel S, Elfil M, Aravala S, Bayoumi A, Patel A, Sinha R, Tinaz S. Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease. Brain Imaging And Behavior 2022, 17: 161-171. PMID: 36434490, PMCID: PMC10050121, DOI: 10.1007/s11682-022-00749-z.Peer-Reviewed Original ResearchConceptsImagery trainingFunctional connectivity changesMild Parkinson's diseaseVisual imagery trainingMental imagery trainingComplex cognitive processesConnectivity changesMotor imagery trainingBrain functional connectivity changesFunctional connectivity characteristicsExecutive processesMental imageryCognitive processesPerceptual experienceNeural correlatesBrain mechanismsImagery practiceImagery contentSensorimotor processesNeuropsychiatric patient populationsMotor functionMotor actsMotor enhancementBrain areasParkinson's disease