2011
Progressive Familial Intrahepatic Cholestasis (PFIC) Type 1, 2, and 3: A Review of the Liver Pathology Findings
Morotti R, Suchy F, Magid M. Progressive Familial Intrahepatic Cholestasis (PFIC) Type 1, 2, and 3: A Review of the Liver Pathology Findings. Seminars In Liver Disease 2011, 31: 003-010. PMID: 21344347, DOI: 10.1055/s-0031-1272831.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphatasesATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 11ATP-Binding Cassette TransportersCholestasis, IntrahepaticDisease ProgressionGenetic Predisposition to DiseaseHeredityHumansLiverPhenotypePrognosisTerminology as TopicConceptsProgressive familial intrahepatic cholestasis type 1Intrahepatic cholestatic diseasesLiver pathology findingsCharacteristic pathologic featuresAutosomal recessive hereditary diseaseBile acid formationRecessive hereditary diseaseLiver histologyPathologic featuresHepatocellular originPathology findingsCholestatic diseaseDisease progressionFIC1 deficiencyMDR3 deficiencyBSEP deficiencyType 1DiseaseHereditary diseaseFirst descriptionDeficiencySpecific genotypesMolecular studiesCholestasisComplications
2009
Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient
Miloh T, Magid M, Iyer K, Kerkar N, Morotti R. Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient. Seminars In Liver Disease 2009, 29: 134-138. PMID: 19235665, DOI: 10.1055/s-0029-1202551.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlanine TransaminaseAntiviral AgentsAspartate AminotransferasesBiopsyChronic DiseaseEpstein-Barr Virus InfectionsGraft RejectionHepatolenticular DegenerationHumansImmunosuppressive AgentsLiverLiver TransplantationMaleReoperationTreatment OutcomeUp-RegulationVasculitisVenulesViral LoadConceptsCentral perivenulitisChronic rejectionLiver transplantationPolymerase chain reactionModerate acute cellular rejectionAcute cellular rejectionFulminant Wilson's diseaseAcute rejectionCellular rejectionEBV seroconversionImmunosuppressive treatmentLiver transaminasesLiver biopsyPediatric patientsAntiviral therapyCase reportNaive statusWilson's diseaseChain reactionTransplantationDiseaseWeeksSubsequent increaseRejectionImmunosuppression
2006
Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis
Sinha J, Morotti R, Norton K, Gold D, Shneider B. Cystic Fibrosis in an Adolescent Being Evaluated for Primary Sclerosing Cholangitis. Seminars In Liver Disease 2006, 26: 080-084. PMID: 16496236, DOI: 10.1055/s-2006-933566.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisWhite blood cell countMagnetic resonance cholangiogramMagnetic resonance cholangiopancreatographyHistory of hypothyroidismSclerosing cholangitisExtrahepatic biliary systemBiliary cirrhosisBile ductPortal tractsCystic fibrosisAlanine aminotransferaseAspartate aminotransferaseFatty pancreasMuscle antibodiesHepatic ductLiver diseasePathologic findingsPersistent elevationBiliary systemPercutaneous liver needle biopsyHepatitis B surface antigenHepatitis B surface antibodyAntinuclear antibody analysisAntismooth muscle antibodies
2001
LIVER PATHOLOGY IN CHILDREN WITH AIDS: A COMPARISON BETWEEN THE SOUTH AMERICAN AND NORTH AMERICAN POPULATION
Morotti R, Tata M, Drut R, Siminovich S, Menezes D, Guitierrez M, Kahn E. LIVER PATHOLOGY IN CHILDREN WITH AIDS: A COMPARISON BETWEEN THE SOUTH AMERICAN AND NORTH AMERICAN POPULATION. Fetal And Pediatric Pathology 2001, 20: 537-545. PMID: 11699578, DOI: 10.1080/pdp.20.6.537.545.Peer-Reviewed Original ResearchConceptsSA childrenGiant cell transformationTime of deathCases of childrenPeliosis hepatisCytomegalovirus infectionLymphoproliferative disordersOpportunistic infectionsHepatic changesPediatric hospitalLiver pathologyRapid progressionHigh prevalenceNA groupLiver tissueAIDSChildrenInfectionAmerican populationCell transformationNorth American populationsHepatisHistopathologicInflammationGroup