2024
Expanding the spectrum of progressive familial intrahepatic cholestasis: A report of 3 cases
Jiao J, Morotti R, Shafizadeh N, Jain D. Expanding the spectrum of progressive familial intrahepatic cholestasis: A report of 3 cases. American Journal Of Clinical Pathology 2024, aqae123. PMID: 39333837, DOI: 10.1093/ajcp/aqae123.Peer-Reviewed Original ResearchProgressive familial intrahepatic cholestasisATP-binding cassette subfamily B member 4Whole-exome sequencingFamilial intrahepatic cholestasisIntrahepatic cholestasisDiagnostic challengeGroup of autosomal recessive disordersAbnormal liver function testsHomozygous splice site variantDrug-induced liver injuryHeterozygous frameshift mutationHeterozygous missense mutationLiver function testsAged 2 monthsAutosomal recessive disorderSplice site variantHistory of alcoholismABCB4 mutationsPediatric ageLiver biopsyClinical historyRecessive disorderLiver injuryMolecular testingHeterogeneous presentation
2009
Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient
Miloh T, Magid M, Iyer K, Kerkar N, Morotti R. Chronic Rejection Preceded by Central Perivenulitis, Rapidly Ensuing After Liver Transplantation in a Pediatric Patient. Seminars In Liver Disease 2009, 29: 134-138. PMID: 19235665, DOI: 10.1055/s-0029-1202551.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlanine TransaminaseAntiviral AgentsAspartate AminotransferasesBiopsyChronic DiseaseEpstein-Barr Virus InfectionsGraft RejectionHepatolenticular DegenerationHumansImmunosuppressive AgentsLiverLiver TransplantationMaleReoperationTreatment OutcomeUp-RegulationVasculitisVenulesViral LoadConceptsCentral perivenulitisChronic rejectionLiver transplantationPolymerase chain reactionModerate acute cellular rejectionAcute cellular rejectionFulminant Wilson's diseaseAcute rejectionCellular rejectionEBV seroconversionImmunosuppressive treatmentLiver transaminasesLiver biopsyPediatric patientsAntiviral therapyCase reportNaive statusWilson's diseaseChain reactionTransplantationDiseaseWeeksSubsequent increaseRejectionImmunosuppression