Machine Learning-Based Prediction of Death and Hospitalization in Patients With Implantable Cardioverter Defibrillators
Rosman L, Lampert R, Wang K, Gehi A, Dziura J, Salmoirago-Blotcher E, Brandt C, Sears S, Burg M. Machine Learning-Based Prediction of Death and Hospitalization in Patients With Implantable Cardioverter Defibrillators. Journal Of The American College Of Cardiology 2024 PMID: 39570241, DOI: 10.1016/j.jacc.2024.09.006.Peer-Reviewed Original ResearchImplantable cardioverter-defibrillatorYear of device implantationAll-cause mortalityCardiac resynchronization therapyDeath/HF hospitalizationValidation cohortHeart failureDevice implantationTime of ICD implantationArea under the receiver-operating characteristic curveMedian follow-upReceiver-operating characteristic curvePredicting all-cause mortalityImplantable cardioverter-defibrillator patientsVeterans Health AdministrationPersonalized risk estimatesImplantable cardioverter defibrillatorResynchronization therapyBaseline demographicsICD implantationTraining cohortTrajectories of individual patientsProspective studyComposite outcomeContinuum of riskAutonomic reactivity to mental stress is associated with cardiovascular mortality
Shah A, Vaccarino V, Moazzami K, Almuwaqqat Z, Garcia M, Ward L, Elon L, Ko Y, Sun Y, Pearce B, Raggi P, Bremner J, Lampert R, Quyyumi A, Shah A. Autonomic reactivity to mental stress is associated with cardiovascular mortality. European Heart Journal Open 2024, 4: oeae086. PMID: 39588213, PMCID: PMC11588410, DOI: 10.1093/ehjopen/oeae086.Peer-Reviewed Original ResearchHazard ratioCardiovascular diseaseHigher CVD mortality riskAssociated with CVD mortalityHeart rate variabilityCardiovascular disease risk factorsCVD mortality riskCardiovascular disease mortalityCardiovascular disease deathsCardiovascular disease outcomesCause-specific survival modelsAssociated with cardiovascular mortalityAll-cause mortalityCVD causeAssociated with HRCVD mortalityMental stress testMeasure of autonomic dysfunctionMortality riskAssess autonomic functionAutonomic dysfunctionCardiovascular mortalityStable cardiovascular diseaseRisk factorsPooled cohort