2023
Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2019
Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose
Ormseth CH, Maciel CB, Zhou SE, Barden MM, Miyares LC, Beekman RB, Gilmore EJ, Greer DM. Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose. Resuscitation 2019, 139: 9-16. PMID: 30965094, DOI: 10.1016/j.resuscitation.2019.04.004.Peer-Reviewed Original ResearchConceptsCardiac arrestNeurological recoveryClinical characteristicsDrug overdoseBrain deathCerebral Performance Category scoreCA casesFavorable neurological recoverySimilar neurological recoveryLarge prospective studiesPositive toxicology screenRankin Scale scorePotential treatment optionSingle academic institutionBystander cardiopulmonary resuscitationHospital dischargeInpatient mortalitySuccessful resuscitationToxicology screenProspective studyTreatment optionsMedical recordsMedication administrationCardiopulmonary resuscitationRetrospective analysis