2020
Apophenia as the Disposition to False Positives: A Unifying Framework for Openness and Psychoticism
Blain S, Longenecker J, Grazioplene R, Klimes-Dougan B, DeYoung C. Apophenia as the Disposition to False Positives: A Unifying Framework for Openness and Psychoticism. Journal Of Psychopathology And Clinical Science 2020, 129: 279-292. PMID: 32212749, PMCID: PMC7112154, DOI: 10.1037/abn0000504.Peer-Reviewed Original ResearchConceptsPositive symptomsOpenness aspectsEmotion recognition taskTheory of mindReport indicatorsWord association taskFalse positive error rateAuditory signal detectionStructural equation modelComputerized tasksPositive schizotypyAssociation taskFalse positive errorsMental contentRecognition taskNormal personality variationDigit identificationPersonality traitsPromising constructPersonality variationPsychosis spectrumPsychoticismSample 2ApopheniaSample 1
2019
Toward a Neural Model of the Openness-Psychoticism Dimension: Functional Connectivity in the Default and Frontoparietal Control Networks
Blain S, Grazioplene R, Ma Y, DeYoung C. Toward a Neural Model of the Openness-Psychoticism Dimension: Functional Connectivity in the Default and Frontoparietal Control Networks. Schizophrenia Bulletin 2019, 46: 540-551. PMID: 31603227, PMCID: PMC7147581, DOI: 10.1093/schbul/sbz103.Peer-Reviewed Original ResearchConceptsFrontoparietal networkFunctional connectivityFunctional magnetic resonance imagingFrontoparietal control networkState functional magnetic resonance imagingIntelligenceNeural modelIntrinsic connectivity networksMeasures of psychoticismHuman Connectome ProjectStructural equation modelingNetworkCognitive controlNeural correlatesPsychosis pronenessLatter networkCognitive deficitsNetwork coherenceConnectome ProjectControl networkEquation modelingPsychosis riskConnectivityStructural correlates of the orbitofrontal cortex and amygdala and personality in female adolescents
Delaparte L, Bartlett E, Grazioplene R, Perlman G, Gardus J, DeLorenzo C, Klein D, Kotov R. Structural correlates of the orbitofrontal cortex and amygdala and personality in female adolescents. Psychophysiology 2019, 56: e13376. PMID: 30942481, PMCID: PMC6650330, DOI: 10.1111/psyp.13376.Peer-Reviewed Original ResearchConceptsMedial orbitofrontal cortexOrbitofrontal cortexT1-weighted structural MRIHigher white matter integrityCritical neurodevelopmental periodMultimodal neuroimaging techniquesWhite matter integrityNeurodevelopmental periodAmygdala volumeCortical thicknessBrain regionsStructural MRIUncinate fasciculusFractional anisotropyNeuroimaging techniquesCortexAdolescent girlsStructural correlatesFemale adolescentsDiffusion tensorAmygdalaAdolescenceAssociationAdult samplesHigh neuroticism
2016
White Matter Correlates of Psychosis-Linked Traits Support Continuity Between Personality and Psychopathology
Grazioplene R, Chavez R, Rustichini A, DeYoung C. White Matter Correlates of Psychosis-Linked Traits Support Continuity Between Personality and Psychopathology. Journal Of Psychopathology And Clinical Science 2016, 125: 1135-1145. PMID: 27819473, PMCID: PMC5117638, DOI: 10.1037/abn0000176.Peer-Reviewed Original ResearchConceptsWhite matter correlatesWhite matter connectivity patternsWhite matter differencesPsychotic spectrum disordersWhite matter connectivityWhite matter microstructureGeneral populationPsychotic disordersProtective roleBrain structuresSubclinical levelsLarge community sampleNeural structuresCommunity sampleConnectivity patternsDisordersEndophenotype studiesSpectrum disorderBiological supportCorrelates
2015
Functional Coherence of Insula Networks Is Associated With Externalizing Behavior
Abram S, Wisner K, Grazioplene R, Krueger R, MacDonald A, DeYoung C. Functional Coherence of Insula Networks Is Associated With Externalizing Behavior. Journal Of Psychopathology And Clinical Science 2015, 124: 1079-1091. PMID: 26301974, PMCID: PMC4658249, DOI: 10.1037/abn0000078.Peer-Reviewed Original ResearchConceptsIntrinsic connectivity networksGeneral disinhibitionSubstance abuseInsula networksFunctional MRI scansSubstance use problemsInsular cortexMRI scansAmygdala abnormalitiesLarge community sampleNeural synchronyDisinhibitionExternalizing behaviorsCommunity sampleAggression domainExternalizing psychopathologyRegression modelsConnectivity networksRecent studiesAbuseCommunity participantsMaladaptive behaviorsExternalizing Spectrum InventoryOpenness to Experience and Intellect Differentially Predict Creative Achievement in the Arts and Sciences
Kaufman S, Quilty L, Grazioplene R, Hirsh J, Gray J, Peterson J, DeYoung C. Openness to Experience and Intellect Differentially Predict Creative Achievement in the Arts and Sciences. Journal Of Personality 2015, 84: 248-258. PMID: 25487993, PMCID: PMC4459939, DOI: 10.1111/jopy.12156.Peer-Reviewed Original ResearchConceptsCreative achievementCognitive abilitiesDivergent thinkingGeneral cognitive abilityDual-process theoryIndependent predictive validityOpenness/IntellectCognitive engagementDiscriminant validityPredictive validityDiverse sampleCreativityScientific creativityArtSemantic informationIntellectAchievementOpennessThinkingExtraversionPerformance measuresPersonalityValidityAbilityParticipants
2014
Subcortical intelligence: Caudate volume predicts IQ in healthy adults
Grazioplene R, Ryman S, Gray J, Rustichini A, Jung R, DeYoung C. Subcortical intelligence: Caudate volume predicts IQ in healthy adults. Human Brain Mapping 2014, 36: 1407-1416. PMID: 25491047, PMCID: PMC6869035, DOI: 10.1002/hbm.22710.Peer-Reviewed Original ResearchConceptsCaudate volumeDopamine receptor availabilityHealthy adultsAttentional functionsVerbal abilityLarge independent samplesIQTotal brain volumeSubcortical structuresIndependent samplesIntelligenceBilateral caudate volumesCaudate morphologyBrain volumeReceptor availabilityPositive associationCaudate nucleusAdultsSignificant positive correlationLearningCaudatePositive correlationAssociation
2012
A novel differential susceptibility gene: CHRNA4 and moderation of the effect of maltreatment on child personality
Grazioplene R, DeYoung C, Rogosch F, Cicchetti D. A novel differential susceptibility gene: CHRNA4 and moderation of the effect of maltreatment on child personality. Journal Of Child Psychology And Psychiatry 2012, 54: 872-880. PMID: 23240931, PMCID: PMC3608843, DOI: 10.1111/jcpp.12031.Peer-Reviewed Original Research
2010
Cortical Thickness and Subcortical Gray Matter Reductions in Neuropsychiatric Systemic Lupus Erythematosus
Jung R, Segall J, Grazioplene R, Qualls C, Sibbitt W, Roldan C. Cortical Thickness and Subcortical Gray Matter Reductions in Neuropsychiatric Systemic Lupus Erythematosus. PLOS ONE 2010, 5: e9302. PMID: 20352085, PMCID: PMC2844408, DOI: 10.1371/journal.pone.0009302.Peer-Reviewed Original ResearchConceptsNeuropsychiatric systemic lupus erythematosusSystemic lupus erythematosusNPSLE groupSLE patientsGray matter volumeCortical thicknessLupus erythematosusNeuropsychiatric symptomsMatter volumeCentral nervous system involvementSystemic lupus erythematosus patientsFreeSurfer image analysis suiteLupus erythematosus patientsNervous system involvementSubcortical gray matter volumesGray matter reductionsGroup differencesSubcortical gray matter structuresSubcortical structure volumesRegional gray matter volumeGray matter structuresSLE groupCortical atrophyCortical thinningControl subjectsWhite Matter Integrity, Creativity, and Psychopathology: Disentangling Constructs with Diffusion Tensor Imaging
Jung R, Grazioplene R, Caprihan A, Chavez R, Haier R. White Matter Integrity, Creativity, and Psychopathology: Disentangling Constructs with Diffusion Tensor Imaging. PLOS ONE 2010, 5: e9818. PMID: 20339554, PMCID: PMC2842439, DOI: 10.1371/journal.pone.0009818.Peer-Reviewed Original ResearchConceptsInferior frontal white matterFrontal white matterWhite matter integrityDiffusion tensor imagingFractional anisotropyWhite matterTensor imagingFronto-striatal circuitsFrontal lobe areasYoung adult subjectsSignificant inverse relationshipCortical thicknessNormal subjectsProjection zonesAssociation fibersAdult subjectsBrain regionsWhite matter architectureInverse correlationTesla scannerMetabolite concentrationsLobe areasComposite measurePsychopathologyInverse relationship