2002
Effectiveness of enzyme replacement therapy in 1028 patients with type 1 Gaucher disease after 2 to 5 years of treatment: a report from the Gaucher Registry
Weinreb NJ, Charrow J, Andersson HC, Kaplan P, Kolodny EH, Mistry P, Pastores G, Rosenbloom BE, Scott CR, Wappner RS, Zimran A. Effectiveness of enzyme replacement therapy in 1028 patients with type 1 Gaucher disease after 2 to 5 years of treatment: a report from the Gaucher Registry. The American Journal Of Medicine 2002, 113: 112-119. PMID: 12133749, DOI: 10.1016/s0002-9343(02)01150-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildChild, PreschoolCohort StudiesDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesGaucher DiseaseGlucosylceramidaseHemoglobinsHumansInfusions, IntravenousLiverMalePain MeasurementPlatelet CountRegistriesRisk AssessmentSpleenStatistics, NonparametricTime FactorsTreatment OutcomeConceptsType 1 Gaucher diseaseYears of treatmentEnzyme replacement therapyBone crisesBone painPlatelet countGaucher diseaseGaucher RegistryReplacement therapyMacrophage-targeted enzyme replacement therapyHemoglobin concentrationShort-term efficacyNormal platelet countFirst lysosomal storage disorderAssessment of responseTimes normal sizeBaseline thrombocytopeniaLysosomal storage disorderAnemic patientsSpleen volumeThrombocytopenic patientsSustained responseIntact spleenSerial measurementsPatients
1990
Intravenous albumin infusion is an effective therapy for hyponatraemia in cirrhotic patients with ascites.
McCormick PA, Mistry P, Kaye G, Burroughs AK, McIntyre N. Intravenous albumin infusion is an effective therapy for hyponatraemia in cirrhotic patients with ascites. Gut 1990, 31: 204. PMID: 2311979, PMCID: PMC1378381, DOI: 10.1136/gut.31.2.204.Peer-Reviewed Original ResearchMeSH KeywordsAgedAlbuminsFemaleHumansHyponatremiaInfusions, IntravenousLiver CirrhosisMaleMiddle AgedConceptsIntravenous albumin infusionAlbumin infusionEffective therapyDecompensated liver diseaseFulminant hepatitis BLiver transplantationCirrhotic patientsHepatitis BSevere hyponatraemiaLiver diseaseIntravenous infusionHyponatraemiaPatientsPreliminary experienceInfusionCirrhosisAscitesTherapyTreatmentSurgeryTransplantationDisease