Long-Term Outcomes of Liver Transplantation in Type 1 Gaucher Disease
Ayto RM, Hughes DA, Jeevaratnam P, Rolles K, Burroughs AK, Mistry PK, Mehta AB, Pastores GM. Long-Term Outcomes of Liver Transplantation in Type 1 Gaucher Disease. American Journal Of Transplantation 2010, 10: 1934-1939. PMID: 20659098, DOI: 10.1111/j.1600-6143.2010.03168.x.Peer-Reviewed Original ResearchConceptsEnzyme replacement therapyLiver transplantationGaucher diseaseLong-term enzyme replacement therapyEnd-stage liver diseaseType 1 Gaucher's diseaseSevere hepatic impairmentOrthotopic liver transplantationSuccessful liver transplantationLife-saving treatmentPrevalent lysosomal storage disorderHepatic impairmentLysosomal storage disorderYears postprocedureLiver failureLiver diseaseTerm outcomesReplacement therapyExcellent outcomesDemonstrable efficacyPatientsTransplantationPathological manifestationsDiseaseStorage disorder