2000
Using a Computer Database to Monitor Compliance With Pharmacotherapeutic Guidelines for Schizophrenia
Chen RS, Nadkarni PM, Levin FL, Miller PL, Erdos J, Rosenheck RA. Using a Computer Database to Monitor Compliance With Pharmacotherapeutic Guidelines for Schizophrenia. Psychiatric Services 2000, 51: 791-794. PMID: 10828112, DOI: 10.1176/appi.ps.51.6.791.Peer-Reviewed Original ResearchConceptsPatient Outcomes Research TeamAcute episodePrescription dataSchizophrenia Patient Outcomes Research TeamVeterans Affairs Medical CenterTrial of clozapinePercent of patientsFirst-line treatmentPatient prescription dataPharmacotherapeutic guidelinesPharmacotherapeutic recommendationsAdequate trialConventional antipsychoticsConventional medicationsConventional regimensOutpatient visitsAntipsychotic regimenTreatment recommendationsSymptom episodesMedical CenterPatientsClozapineConventional drugsComputerized databasePORT recommendations
1992
Fast Computation of Genetic Likelihoods on Human Pedigree Data
Goradia T, Lange K, Miller P, Nadkarni P. Fast Computation of Genetic Likelihoods on Human Pedigree Data. Human Heredity 1992, 42: 42-62. PMID: 1555846, DOI: 10.1159/000154045.Peer-Reviewed Original ResearchConceptsHuman pedigree dataNetwork of workstationsLarge-scale computationsHardware techniquesParallel machinesComputational speedDifferent architecturesLinkage problemFast computationVectorized versionComputationFast calculationLarge numberParallelizationSupercomputersVectorizationComplete phenotypingWorkstationsArchitectureGenetic likelihoodMachineNetworkVersionNew methodSubstantial improvement