2009
Automated Database Mediation Using Ontological Metadata Mappings
Marenco L, Wang R, Nadkarni P. Automated Database Mediation Using Ontological Metadata Mappings. Journal Of The American Medical Informatics Association 2009, 16: 723-737. PMID: 19567801, PMCID: PMC2744723, DOI: 10.1197/jamia.m3031.Peer-Reviewed Original ResearchConceptsCross-database queriesHigh-level rulesEnforcement of constraintsDatabase MediationDatabase federationsDatabase ontologyExtended metadataGranularity levelsMetadata mappingBiomedical ontologiesDifferent granularitiesFramework simplifiesCategories of dataMaintenance of systemsMapping rulesQueriesDatabase informationGranularity of representationGlobal vocabularyOntologyGranularityIntegrator systemMetadataDatabaseSNOMED
2007
SenseLab: new developments in disseminating neuroscience information
Crasto CJ, Marenco LN, Liu N, Morse TM, Cheung KH, Lai PC, Bahl G, Masiar P, Lam HY, Lim E, Chen H, Nadkarni P, Migliore M, Miller PL, Shepherd GM. SenseLab: new developments in disseminating neuroscience information. Briefings In Bioinformatics 2007, 8: 150-162. PMID: 17510162, PMCID: PMC2756159, DOI: 10.1093/bib/bbm018.Peer-Reviewed Original Research
2004
QIS: A Framework for Biomedical Database Federation
Marenco L, Wang TY, Shepherd G, Miller PL, Nadkarni P. QIS: A Framework for Biomedical Database Federation. Journal Of The American Medical Informatics Association 2004, 11: 523-534. PMID: 15298995, PMCID: PMC524633, DOI: 10.1197/jamia.m1506.Peer-Reviewed Original ResearchConceptsNetwork-based serversHeterogeneous data sourcesRobust data integrationIntegration serverOntology serverDatabase federationsSource serverNeuroscience databasesData integrationMediator frameworkServerData elementsQueriesData sourcesMetadataPrototype stageStandard technologyIntegrator systemGenomic databasesFrameworkDatabaseOntologyArchitectureSchemaTechnological expertiseIntegration of Web-based and PC-based Clinical Research Databases
Brandt CA, Sun K, Charpentier P, Nadkarni PM. Integration of Web-based and PC-based Clinical Research Databases. Methods Of Information In Medicine 2004, 43: 287-295. PMID: 15227559, DOI: 10.1055/s-0038-1633870.Peer-Reviewed Original ResearchConceptsDatabase applicationsClinical study data management systemsIntegration of applicationsCommon semantic modelData management systemWeb-based repositoryClinical research databaseSchema conflictsSharing of featuresData managementMapping schemaSemantic modelDifferent operating environmentsModel unificationManagement systemIntegration effortsOperating environmentArea of applicabilityData collectionMajor benefitsSimilar purposesIntegrationApplicationsCritical conflictsData libraries
2003
Text mining neuroscience journal articles to populate neuroscience databases
Crasto CJ, Marenco LN, Migliore M, Mao B, Nadkarni PM, Miller P, Shepherd GM. Text mining neuroscience journal articles to populate neuroscience databases. Neuroinformatics 2003, 1: 215-237. PMID: 15046245, DOI: 10.1385/ni:1:3:215.Peer-Reviewed Original ResearchConceptsNeuroscience databasesNatural language textPre-processing stepDatabase architectureLanguage textRetrieval resultsDatabase keywordsSemantic contextBibliography databasesNeuroscience articlesTest setTwo-step approachFirst stepDatabaseExpertsArchitectureSoftwareKnowledgebaseSecond stepNeuroscienceSenseLabKeywordsContinual improvementStepAccuracyIntegrating Query of Relational and Textual Data in Clinical Databases: A Case Study
Fisk JM, Mutalik P, Levin FW, Erdos J, Taylor C, Nadkarni P. Integrating Query of Relational and Textual Data in Clinical Databases: A Case Study. Journal Of The American Medical Informatics Association 2003, 10: 21-38. PMID: 12509355, PMCID: PMC150357, DOI: 10.1197/jamia.m1133.Peer-Reviewed Original ResearchConceptsRelational database management systemInformation retrievalDatabase management systemClinical data martCommodity softwareFuzzy searchingText indexingRelational searchTextual dataData martIR softwareBoolean searchManagement systemMedical textsSoftwareSearchingDocumentsQueriesTextIndexingClinical databaseCase studyIR facilitiesRetrievalVendors
2001
Integration of Multidisciplinary Sensory Data
Miller P, Nadkarni P, Singer M, Marenco L, Hines M, Shepherd G. Integration of Multidisciplinary Sensory Data. Journal Of The American Medical Informatics Association 2001, 8: 34-48. PMID: 11141511, PMCID: PMC134590, DOI: 10.1136/jamia.2001.0080034.Peer-Reviewed Original ResearchConceptsNeuroinformatics researchFlexible data modelDiverse heterogeneous dataHuman Brain ProjectNew informatics technologiesHeterogeneous dataData modelSensory dataRelated toolsInformatics technologiesBrain ProjectBuilding databaseSingle unifying frameworkUnifying frameworkProject approachIntegrationComputer modelEasing the transition between attribute-value databases and conventional databases for scientific data.
Nadkarni P, Marenco L. Easing the transition between attribute-value databases and conventional databases for scientific data. AMIA Annual Symposium Proceedings 2001, 483-7. PMID: 11825235, PMCID: PMC2243470.Peer-Reviewed Original ResearchMeSH KeywordsDatabase Management SystemsDatabases as TopicSystems IntegrationUser-Computer InterfaceConceptsEAV/CRData transfer toolsData transfer programProgrammer interventionConventional databasesLegacy systemsDB technologyDevelopment frameworkGeneric toolData sourcesDifferent representationsConventional dataAnalytical packageDatabaseScientific dataTransfer toolsScientific databasesTransfer taskToolProgrammingTaskCurrent limitationsWide varietyTechnologyFramework
1999
Neuronal database integration: the Senselab EAV data model.
Marenco L, Nadkarni P, Skoufos E, Shepherd G, Miller P. Neuronal database integration: the Senselab EAV data model. AMIA Annual Symposium Proceedings 1999, 102-6. PMID: 10566329, PMCID: PMC2232788.Peer-Reviewed Original ResearchMeSH KeywordsDatabases, FactualHumansHypermediaInformation Storage and RetrievalInternetNervous SystemSystems Integration
1996
ModelDB: An Environment for Running and Storing Computational Models and Their Results Applied to Neuroscience
Peterson B, Healy M, Nadkarni P, Miller P, Shepherd G. ModelDB: An Environment for Running and Storing Computational Models and Their Results Applied to Neuroscience. Journal Of The American Medical Informatics Association 1996, 3: 389-398. PMID: 8930855, PMCID: PMC116323, DOI: 10.1136/jamia.1996.97084512.Peer-Reviewed Original ResearchConceptsWorld Wide Web interfaceCluster of databasesHuman Brain ProjectWeb interfaceComputational modelIndividual databasesSmall databaseDatabase developmentBrain ProjectComplex informationRelated databasesFormal mannerVast quantitiesSystem functionDiverse sourcesDatabaseInformationWebProjectResearch groupsInitial approachPilot projectIssuesGeneral issuesTechnology
1995
Internet-based Support for Bioscience Research: A Collaborative Genome center for Human Chromosome 12
Miller P, Nadkarni P, Kidd K, Cheung K, Ward D, Banks A, Bray-Ward P, Cupelli L, Herdman V, Marondel I, Montcomery K, Renault B, Yoon S, Krauter K, Kucherlapati R. Internet-based Support for Bioscience Research: A Collaborative Genome center for Human Chromosome 12. Journal Of The American Medical Informatics Association 1995, 2: 351-364. PMID: 8581551, PMCID: PMC116278, DOI: 10.1136/jamia.1995.96157828.Peer-Reviewed Original ResearchMeSH KeywordsChromosome MappingChromosomes, Artificial, YeastChromosomes, Human, Pair 12Computer Communication NetworksConnecticutData DisplayDatabases, FactualGenetic MarkersGenome, HumanHumansInterinstitutional RelationsLocal Area NetworksModels, GeneticNew York CityOrganizational ObjectivesSoftware DesignSystems IntegrationUser-Computer InterfaceConceptsUser-friendly front endInternet-based supportExternal databasesMedical informaticsGenome CenterGenome informaticsDatabase programMapping communityCandidate mapsInformaticsAssembly toolsAreas of bioscienceFront endDatabaseServerSybaseSuch supportCase studySetToolBioscience researchCertain issuesClientsTechnologySupportNetwork-based informatics support of research collaborations in the Human Genome Project and the Human Brain Project.
Miller P, Nadkarni P, Kucherlapati R, Krauter K, Kidd K, Ward D, Shepherd G, Berkowicz D. Network-based informatics support of research collaborations in the Human Genome Project and the Human Brain Project. Medinfo. 1995, 8 Pt 2: 1541-4. PMID: 8591495.Peer-Reviewed Original Research