2004
QIS: A Framework for Biomedical Database Federation
Marenco L, Wang TY, Shepherd G, Miller PL, Nadkarni P. QIS: A Framework for Biomedical Database Federation. Journal Of The American Medical Informatics Association 2004, 11: 523-534. PMID: 15298995, PMCID: PMC524633, DOI: 10.1197/jamia.m1506.Peer-Reviewed Original ResearchConceptsNetwork-based serversHeterogeneous data sourcesRobust data integrationIntegration serverOntology serverDatabase federationsSource serverNeuroscience databasesData integrationMediator frameworkServerData elementsQueriesData sourcesMetadataPrototype stageStandard technologyIntegrator systemGenomic databasesFrameworkDatabaseOntologyArchitectureSchemaTechnological expertise
2003
Text mining neuroscience journal articles to populate neuroscience databases
Crasto CJ, Marenco LN, Migliore M, Mao B, Nadkarni PM, Miller P, Shepherd GM. Text mining neuroscience journal articles to populate neuroscience databases. Neuroinformatics 2003, 1: 215-237. PMID: 15046245, DOI: 10.1385/ni:1:3:215.Peer-Reviewed Original ResearchConceptsNeuroscience databasesNatural language textPre-processing stepDatabase architectureLanguage textRetrieval resultsDatabase keywordsSemantic contextBibliography databasesNeuroscience articlesTest setTwo-step approachFirst stepDatabaseExpertsArchitectureSoftwareKnowledgebaseSecond stepNeuroscienceSenseLabKeywordsContinual improvementStepAccuracyTemporal query of attribute-value patient data: utilizing the constraints of clinical studies
Deshpande AM, Brandt C, Nadkarni PM. Temporal query of attribute-value patient data: utilizing the constraints of clinical studies. International Journal Of Medical Informatics 2003, 70: 59-77. PMID: 12706183, PMCID: PMC2987270, DOI: 10.1016/s1386-5056(02)00183-1.Peer-Reviewed Original ResearchConceptsClinical study data management systemsTemporal queriesClinical patient record systemsClinical data storageData management systemPatient record systemQuery algorithmData storageTemporal operatorsClinical studiesQueriesManagement systemGroup of patientsRecord systemEffect of therapyTemporal computationAdverse eventsRelational formsPatient dataLogistic reasonsArchitectureValue modelAlgorithm
2000
WebEAV
Nadkarni P, Brandt C, Marenco L. WebEAV. Journal Of The American Medical Informatics Association 2000, 7: 343-356. PMID: 10887163, PMCID: PMC61439, DOI: 10.1136/jamia.2000.0070343.Peer-Reviewed Original ResearchConceptsWeb development environmentWeb application developmentUser interface issuesClient-server technologyValue databaseWeb technologiesApplication developmentEntity attributesWeb developmentDevelopment environmentWeb interfaceGeneric frameworkInterface issuesComplex systemsFront endDatabaseTechnologyMetadataDevelopersSuitable examplesArchitectureTaskFeaturesFrameworkVehicles
1992
Fast Computation of Genetic Likelihoods on Human Pedigree Data
Goradia T, Lange K, Miller P, Nadkarni P. Fast Computation of Genetic Likelihoods on Human Pedigree Data. Human Heredity 1992, 42: 42-62. PMID: 1555846, DOI: 10.1159/000154045.Peer-Reviewed Original ResearchConceptsHuman pedigree dataNetwork of workstationsLarge-scale computationsHardware techniquesParallel machinesComputational speedDifferent architecturesLinkage problemFast computationVectorized versionComputationFast calculationLarge numberParallelizationSupercomputersVectorizationComplete phenotypingWorkstationsArchitectureGenetic likelihoodMachineNetworkVersionNew methodSubstantial improvement