2006
Organization of Flaviviral Replicase Proteins in Virus‐Induced Membranes: a Role for NS1′ in Japanese Encephalitis Virus RNA Synthesis
Satchidanandam V, Uchil PD, Kumar P. Organization of Flaviviral Replicase Proteins in Virus‐Induced Membranes: a Role for NS1′ in Japanese Encephalitis Virus RNA Synthesis. Novartis Foundation Symposia 2006, 277: 136-148. PMID: 17319159, DOI: 10.1002/0470058005.ch10.Peer-Reviewed Original ResearchConceptsJapanese encephalitis virusNuclear Localization of Flavivirus RNA Synthesis in Infected Cells
Uchil P, Kumar A, Satchidanandam V. Nuclear Localization of Flavivirus RNA Synthesis in Infected Cells. Journal Of Virology 2006, 80: 5451-5464. PMID: 16699025, PMCID: PMC1472159, DOI: 10.1128/jvi.01982-05.Peer-Reviewed Original ResearchConceptsReplicase proteinsReplication complexMembrane-bound replication complexesRNA synthesisViral replicase proteinsRNA-dependent RNA polymerase activityViral replication complexFlavivirus RNA synthesisCell nucleus functionsRNA polymerase activityReplicase complexHost cytoplasmNuclear matrixNuclear localizationNuclear locationPeripheral laminaIsolated nucleiImmunoelectron microscopyPolymerase activityJapanese encephalitis virusFlavivirus RNAInfected cellsProteinAbsolute requirementViral RNA
2003
Screening for T cell-eliciting proteins of Japanese encephalitis virus in a healthy JE-endemic human cohort using recombinant baculovirus-infected insect cell preparations
Kumar P, Uchil PD, Sulochana P, Nirmala G, Chandrashekar R, Haridattatreya M, Satchidanandam V. Screening for T cell-eliciting proteins of Japanese encephalitis virus in a healthy JE-endemic human cohort using recombinant baculovirus-infected insect cell preparations. Archives Of Virology 2003, 148: 1569-1591. PMID: 12898332, DOI: 10.1007/s00705-003-0118-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, ViralBaculoviridaeCells, CulturedCohort StudiesEncephalitis Virus, JapaneseEncephalitis, JapaneseEndemic DiseasesFemaleHumansImmunologic MemoryLymphocyte ActivationMaleRecombinant ProteinsRNA HelicasesSerine EndopeptidasesSpodopteraT-LymphocytesViral Nonstructural ProteinsViral ProteinsConceptsJapanese encephalitis virusCell-mediated immune responsesT cell responsesImmune responseJEV infectionT cellsCell responsesEncephalitis virusAdaptive T cell responsesHuman cohortsTh1 immune responseMemory T cellsCell preparationsImmune controlHealthy individualsCohortWhole cell preparationsViral proteinsInfectionNS3 proteinImportant targetVirusCritical determinantNS1NS5 protein