2017
Cdk1‐interacting protein Cip1 is regulated by the S phase checkpoint in response to genotoxic stress
Zhang Z, Ren P, Vashisht AA, Wohlschlegel JA, Quintana DG, Zeng F. Cdk1‐interacting protein Cip1 is regulated by the S phase checkpoint in response to genotoxic stress. Genes To Cells 2017, 22: 850-860. PMID: 28771906, PMCID: PMC5643225, DOI: 10.1111/gtc.12518.Peer-Reviewed Original ResearchConceptsS-phase checkpointGenotoxic stressPhase checkpointG1 cyclin Cln2Rad53-dependent mannerCDK1 inhibitorS-phase checkpoint responseYeast Saccharomyces cerevisiaeMec1-dependent mannerATM/ATRDe novo protein synthesisCell cycle progressionDependent kinase inhibitorNovo protein synthesisTQ motifsChromosome replicationEukaryotic cellsReplication stressCheckpoint responseChromosomal replicationDownstream kinasesSaccharomyces cerevisiaeGenomic instabilityCycle progressionG1 cyclins
2016
Identification of YPL014W (Cip1) as a novel negative regulator of cyclin‐dependent kinase in Saccharomyces cerevisiae
Ren P, Malik A, Zeng F. Identification of YPL014W (Cip1) as a novel negative regulator of cyclin‐dependent kinase in Saccharomyces cerevisiae. Genes To Cells 2016, 21: 543-552. PMID: 27005485, DOI: 10.1111/gtc.12361.Peer-Reviewed Original ResearchMeSH KeywordsCDC2 Protein KinaseCell CycleCell Cycle ProteinsMutationProteomicsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsConceptsCyclin-dependent kinasesNovel negative regulatorNegative regulatorCell division cycle progressionCycle progressionCell cycleModel eukaryotic organism SaccharomycesSingle cyclin-dependent kinaseCdk1-dependent mannerWild-type cellsBlocks cell cycle progressionCell cycle progressionClb5-Cdk1Organism SaccharomycesEukaryotic cellsGenomic instabilityUnscheduled proliferationKinaseCIP1SaccharomycesCDK1RegulatorSic1CellsCerevisiae