Studies on the role of the thymus and T cells in the in vivo suppression of delayed hypersensitivity (desensitization): radiosensitivity of the mechanism inducing nonspecific anergy.
Thestrup-Pedersen K, Dwyer J, Askenase P. Studies on the role of the thymus and T cells in the in vivo suppression of delayed hypersensitivity (desensitization): radiosensitivity of the mechanism inducing nonspecific anergy. The Journal Of Immunology 1977, 118: 1665-71. PMID: 300755, DOI: 10.4049/jimmunol.118.5.1665.Peer-Reviewed Original ResearchConceptsT cellsDelayed hypersensitivitySuppression of delayed hypersensitivityDoses of whole-body irradiationNonspecific desensitizationMature T cellsWhole-body irradiationMono-nuclear cellsIn vivo suppressionThymic weightImmunoregulatory mechanismsPeripheral bloodRadiosensitive cellsAssociated with 1AnergySmall dosesDecreased responseGuinea pigsSkin sitesDesensitizationAntigenDesensitized stateConcanavalin AHypersensitivityCells