2011
Participation of Inkt Cells in the Early and Late Components of Tc1‐Mediated DNFB Contact Sensitivity: Cooperative Role of γδ‐T Cells
Askenase PW, Majewska‐Szczepanik M, Kerfoot S, Szczepanik M. Participation of Inkt Cells in the Early and Late Components of Tc1‐Mediated DNFB Contact Sensitivity: Cooperative Role of γδ‐T Cells. Scandinavian Journal Of Immunology 2011, 73: 465-477. PMID: 21272050, DOI: 10.1111/j.1365-3083.2011.02522.x.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsDermatitis, ContactDinitrofluorobenzeneFemaleFlow CytometryImmunizationImmunophenotypingInterferon-gammaMiceMice, Inbred BALB CMice, Inbred C57BLMice, Inbred CBAMice, KnockoutNatural Killer T-CellsReceptors, Antigen, T-Cell, alpha-betaSpecific Pathogen-Free OrganismsT-Lymphocytes, Cytotoxic
2009
Epicutaneous Immunization with Protein Antigen in the Presence of TLR4 Ligand Induces TCRαβ+CD4+ T Contrasuppressor Cells That Reverse Skin-Induced Suppression of Th1-Mediated Contact Sensitivity
Ptak W, Majewska M, Bryniarski K, Ptak M, Lobo FM, Zając K, Askenase PW, Szczepanik M. Epicutaneous Immunization with Protein Antigen in the Presence of TLR4 Ligand Induces TCRαβ+CD4+ T Contrasuppressor Cells That Reverse Skin-Induced Suppression of Th1-Mediated Contact Sensitivity. The Journal Of Immunology 2009, 182: 837-850. PMID: 19124727, DOI: 10.4049/jimmunol.182.2.837.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, CutaneousAnimalsCD4-Positive T-LymphocytesCells, CulturedContraindicationsDermatitis, ContactImmune ToleranceImmunizationLigandsLipopolysaccharidesMaleMiceMice, Inbred BALB CMice, Inbred CBAMice, KnockoutMice, TransgenicPatch TestsReceptors, Antigen, T-Cell, alpha-betaSkinTh1 CellsToll-Like Receptor 4TrinitrobenzenesConceptsEpicutaneous immunizationEffector cellsIL-12Effector phaseT cellsIFN-gammaTC cellsContrasuppressor T cellsCS effector cellsIL-12 neutralizationSkin-induced suppressionContact sensitivity reactionTh1 effector cellsTLR4 ligand LPSMechanism of actionEC immunizationSuppressor CD4Th1 CD4Regulatory cellsRIL-12TLR4 ligandIL-6Contact sensitivityLigand LPSINF-gamma
1976
Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity.
Askenase P. Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity. The Journal Of Immunology 1976, 117: 741-7. PMID: 1085308, DOI: 10.4049/jimmunol.117.3.741.Peer-Reviewed Original ResearchConceptsCell transferIncomplete Freund's adjuvantSkin reactionsCutaneous basophil hypersensitivityGuinea pigsRecipients of cellsNylon wool columnsCell transfer recipientsDelayed skin reactionsT cellsSkin testBasophil responseFreund's adjuvantCellular transferTuberculin hypersensitivitySensitization of recipientsWool columnsBasophil infiltrationHumoral factorsBasophil numbersPassive transferHypersensitivityRecipientsBasophilsDelayed reactionsAntibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs.
Askenase P, Haynes J, Hayden B. Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs. The Journal Of Immunology 1976, 117: 216-24. PMID: 932424, DOI: 10.4049/jimmunol.117.1.216.Peer-Reviewed Original ResearchConceptsCutaneous basophil hypersensitivityCutaneous hypersensitivity reactionsGuinea pigsDelayed hypersensitivityBasophil accumulationProduction of B lymphocytesCutaneous basophil hypersensitivity reactionT lymphocytesKeyhole limpet hemocyanin (KLHB lymphocytesIntradermal injectionDonors 1 weekHypersensitive responseHypersensitivity reactionsPigsSerum antibodiesAntibody production of B lymphocytesHypersensitivityBasophil reactionsImmune serumAntibody productionSerum