2008
Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity
Kerfoot SM, Szczepanik M, Tung JW, Askenase PW. Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity. The Journal Of Immunology 2008, 181: 1717-1727. PMID: 18641308, DOI: 10.4049/jimmunol.181.3.1717.Peer-Reviewed Original ResearchConceptsContact sensitivityB cellsCS initiationInflammatory responseT cell-mediated inflammationProinflammatory T cellsCell-mediated inflammationAdoptive transfer experimentsDelayed-type hypersensitivityAg-specific IgMReceptor gene mutationsSensitized miceVascular activationDeficient recipientsT cellsNovel subsetSomatic hypermutationNovel subpopulationGene mutationsIgMMiceActivation-Induced DeaminaseWT cellsCellsChain gene
1996
Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity.
Geba GP, Ptak W, Anderson GM, Paliwal V, Ratzlaff RE, Levin J, Askenase PW. Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity. The Journal Of Immunology 1996, 157: 557-65. PMID: 8752902, DOI: 10.4049/jimmunol.157.2.557.Peer-Reviewed Original ResearchConceptsMast cell-deficient miceCell-deficient miceDelayed-type hypersensitivityContact sensitivityPlatelet depletionMast cellsCS responsesT cell-mediated immune responsesMast cell-deficient strainsDelayed-type hypersensitivity responseT cell-mediated responsesCell-mediated immune responsesTissue levelsCutaneous sensitivity responsesVasoactive amine serotoninCell-mediated responsesLocal mast cellsMast cell numbersNormal mast cell numbersHypersensitivity responseCutaneous responseImmunologic evidenceBeige miceImmune responseAmine serotonin