Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are ‘The Elephant in the Room’
Askenase PW. Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are ‘The Elephant in the Room’. RNA Biology 2021, 18: 2038-2053. PMID: 33944671, PMCID: PMC8582996, DOI: 10.1080/15476286.2021.1885189.Peer-Reviewed Original ResearchConceptsExtracellular vesiclesAcceptor cellsOuter membrane vesiclesMiRNA transferMolecular chemical changesNano-extracellular vesiclesCargo moleculesExosome transferMembrane vesiclesMiRNAsGenetic expressionDNA expressionExosomesVesiclesCell functionIntracellular effectsFunctional effectsFunctional alterationsMolecular transferCellsPhysiologic processesLight chainExpressionMitochondriaBiology