Antibodies Enhance the Suppressive Activity of Extracellular Vesicles in Mouse Delayed-Type Hypersensitivity
Nazimek K, Bustos-Morán E, Blas-Rus N, Nowak B, Totoń-Żurańska J, Seweryn MT, Wołkow P, Woźnicka O, Szatanek R, Siedlar M, Askenase PW, Sánchez-Madrid F, Bryniarski K. Antibodies Enhance the Suppressive Activity of Extracellular Vesicles in Mouse Delayed-Type Hypersensitivity. Pharmaceuticals 2021, 14: 734. PMID: 34451831, PMCID: PMC8398949, DOI: 10.3390/ph14080734.Peer-Reviewed Original ResearchDelayed-type hypersensitivityMice delayed-type hypersensitivityAntigen-specific antibodiesEffector T cellsT cellsSuppressive activityExtracellular vesiclesAntigen-presenting macrophagesMHC class IIGreat therapeutic potentialMouse modelSuppressive actionCurrent studyMiRNA-150Therapeutic potentialClass IIFlow cytometryExact mechanismAntibodiesParental cellsTherapeutic usageHypersensitivityMacrophagesIntercellular communicationSpecific binding