2011
Stimulatory Lipids Accumulate in the Mouse Liver within 30 min of Contact Sensitization to Facilitate the Activation of Naïve iNKT Cells in a CD1d‐Dependent Fashion
Dey N, Szczepanik M, Lau K, Majewska‐Szczepanik M, Askenase PW. Stimulatory Lipids Accumulate in the Mouse Liver within 30 min of Contact Sensitization to Facilitate the Activation of Naïve iNKT Cells in a CD1d‐Dependent Fashion. Scandinavian Journal Of Immunology 2011, 74: 52-61. PMID: 21352253, DOI: 10.1111/j.1365-3083.2011.02540.x.Peer-Reviewed Original ResearchConceptsHepatic iNKT cellsINKT cellsContact sensitivityHepatic lipidsT cellsB cellsNatural killer T cellsAdoptive transfer techniquesEffector T cellsLiver mononuclear cellsCutaneous inflammatory responseINKT cell activationKiller T cellsMouse liverΑβ T cell receptorAllergic contact dermatitisInnate immune systemRecipient mouse liversSame allergenContact hypersensitivityTopical sensitizationContact sensitizationIgM antibodiesMononuclear cellsIL-4Participation of Inkt Cells in the Early and Late Components of Tc1‐Mediated DNFB Contact Sensitivity: Cooperative Role of γδ‐T Cells
Askenase PW, Majewska‐Szczepanik M, Kerfoot S, Szczepanik M. Participation of Inkt Cells in the Early and Late Components of Tc1‐Mediated DNFB Contact Sensitivity: Cooperative Role of γδ‐T Cells. Scandinavian Journal Of Immunology 2011, 73: 465-477. PMID: 21272050, DOI: 10.1111/j.1365-3083.2011.02522.x.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsDermatitis, ContactDinitrofluorobenzeneFemaleFlow CytometryImmunizationImmunophenotypingInterferon-gammaMiceMice, Inbred BALB CMice, Inbred C57BLMice, Inbred CBAMice, KnockoutNatural Killer T-CellsReceptors, Antigen, T-Cell, alpha-betaSpecific Pathogen-Free OrganismsT-Lymphocytes, Cytotoxic
2008
Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity
Kerfoot SM, Szczepanik M, Tung JW, Askenase PW. Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity. The Journal Of Immunology 2008, 181: 1717-1727. PMID: 18641308, DOI: 10.4049/jimmunol.181.3.1717.Peer-Reviewed Original ResearchConceptsContact sensitivityB cellsCS initiationInflammatory responseT cell-mediated inflammationProinflammatory T cellsCell-mediated inflammationAdoptive transfer experimentsDelayed-type hypersensitivityAg-specific IgMReceptor gene mutationsSensitized miceVascular activationDeficient recipientsT cellsNovel subsetSomatic hypermutationNovel subpopulationGene mutationsIgMMiceActivation-Induced DeaminaseWT cellsCellsChain gene
1979
Involvement of host Fc receptors in antibody-mediated cutaneous basophil hypersensitivity reactions.
Graziano F, Askenase P. Involvement of host Fc receptors in antibody-mediated cutaneous basophil hypersensitivity reactions. The Journal Of Immunology 1979, 123: 1645-52. PMID: 90094, DOI: 10.4049/jimmunol.123.4.1645.Peer-Reviewed Original ResearchConceptsPassive cutaneous anaphylaxisCutaneous basophil hypersensitivityFc receptorsT cellsGuinea pig immune serumBinding to Fc receptorsGamma-globulinCutaneous mast cellsCutaneous basophil hypersensitivity reactionPurified Fc fragmentsB cellsFc fragmentSecretion of moleculesCutaneous responseRabbit IgGHypersensitivity reactionsBovine gamma globulinConcurrent inhibitionGuinea pigsMast cellsSerum antibodiesCutaneous anaphylaxisHeterologous gamma globulinImmune serumSerum