2017
Computerized Cognitive Behavioral Therapy for Insomnia in a Community Health Setting.
Feuerstein S, Hodges SE, Keenaghan B, Bessette A, Forselius E, Morgan PT. Computerized Cognitive Behavioral Therapy for Insomnia in a Community Health Setting. Journal Of Clinical Sleep Medicine 2017, 13: 267-274. PMID: 27784409, PMCID: PMC5263082, DOI: 10.5664/jcsm.6460.Peer-Reviewed Original ResearchMeSH KeywordsCognitive Behavioral TherapyCommunity Health ServicesFemaleHumansMaleMiddle AgedSleep Initiation and Maintenance DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsPittsburgh Sleep Quality IndexCo-occurring mental illnessCognitive behavioral therapyMental illnessBehavioral therapyI groupCommunity mental health centerCommunity health settingsMore psychotropic medicationsSleep Quality IndexComputerized cognitive behavioral therapyMental health care treatmentMental health centersWeekly outpatient sessionsLow socioeconomic statusHealth care treatmentPSQI scoresPsychotropic medicationsCare treatmentActive control groupHealth centersInsomnia treatmentOutpatient sessionsRisk demographicsWeek 6
2016
Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence
Hodges SE, Pittman B, Morgan PT. Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence. Sleep 2016, 40: zsw069. PMID: 28364419, PMCID: PMC5806585, DOI: 10.1093/sleep/zsw069.Peer-Reviewed Original ResearchMeSH KeywordsAdultBenzhydryl CompoundsCocaine-Related DisordersDouble-Blind MethodFemaleHumansMaleMiddle AgedModafinilPerceptionPolysomnographySleepSleep Initiation and Maintenance DisordersWakefulnessWakefulness-Promoting AgentsConceptsChronic cocaine usersSleep state misperceptionWeeks of abstinenceTotal sleep timeOccult insomniaCocaine usersState misperceptionSleep onsetSleep timeCocaine-dependent personsInpatient research facilitySleep latencyDiary questionnairesSleep perceptionPolysomnographic sleep recordingsDiary measurementsAbstinenceTreatment studiesFinal awakeningMisperceptionsNight 3Objective worseningParticipantsInsomniaSleep recordings
2012
Cortical GABA Levels in Primary Insomnia
Morgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G. Cortical GABA Levels in Primary Insomnia. Sleep 2012, 35: 807-814. PMID: 22654200, PMCID: PMC3353043, DOI: 10.5665/sleep.1880.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain ChemistryCase-Control StudiesFemaleGamma-Aminobutyric AcidHumansMagnetic Resonance SpectroscopyMaleMiddle AgedPolysomnographySleep Initiation and Maintenance DisordersConceptsGABA levelsSleep complaintsPrimary insomniaSleep onsetCortical GABA levelsGABA/creatine ratiosOccipital GABA levelsPolysomnographic sleep measuresBrain GABA levelsBody mass indexMain outcome measuresUniversity research clinicPrimary insomnia groupAllostatic responseProton magnetic resonance spectroscopyMaintenance of sleepGABA contentUse of cigarettesUse of caffeineMass indexOutpatient studyCreatine ratioOutcome measuresResearch clinicTwo-group comparison study
2010
A multistudy analysis of the effects of early cocaine abstinence on sleep
Matuskey D, Pittman B, Forselius E, Malison RT, Morgan PT. A multistudy analysis of the effects of early cocaine abstinence on sleep. Drug And Alcohol Dependence 2010, 115: 62-66. PMID: 21144676, PMCID: PMC3081928, DOI: 10.1016/j.drugalcdep.2010.10.015.Peer-Reviewed Original ResearchMeSH KeywordsAdultCocaineCocaine-Related DisordersFemaleHumansMaleMiddle AgedPolysomnographySleepSleep Initiation and Maintenance DisordersSleep StagesSubstance Withdrawal SyndromeTime FactorsYoung Adult
2009
Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans
MORGAN PT, KEHNE JH, SPRENGER KJ, MALISON RT. Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans. Journal Of Sleep Research 2009, 19: 157-164. PMID: 19682231, DOI: 10.1111/j.1365-2869.2009.00757.x.Peer-Reviewed Original ResearchConceptsTotal sleep timeSleep timeMotor learningSleep-dependent motor learningRapid eye movement (REM) sleepLonger total sleep timeGamma-aminobutyric acid receptor complexEye movement sleepREM onset latencyHealthy male subjectsStage 2 sleepMemory consolidationRetrograde effectsTriazolam conditionZolpidem conditionSkill memory consolidationMovement sleepSleep-dependent memory consolidationSufficient dosesHealthy peopleSleep laboratoryPlacebo conditionBenzodiazepine siteOnset latencyMale subjects
2008
Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence
Morgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.Peer-Reviewed Original ResearchConceptsSleep-dependent learningCocaine-dependent personsEffects of lorazepamCognitive effectsCognitive functionMotor learningTotal sleep timeDependent learningImpulsivitySlow-wave sleepCocaine abstinenceSleep latencyAbstinenceSleep timeSleepDependent personsLearningLight sleepCognitionCocaine administrationSedative hypnoticsPilot studyLorazepamParticipantsDifferent GABA
2005
Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomnia
Morgan PT, Pace-Schott EF, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomnia. Drug And Alcohol Dependence 2005, 82: 238-249. PMID: 16260094, DOI: 10.1016/j.drugalcdep.2005.09.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingCocaineCocaine-Related DisordersCognitionHumansLife StyleMiddle AgedPlacebo EffectPlacebosReaction TimeSelf AdministrationSleepSleep Initiation and Maintenance DisordersSmokingWakefulnessConceptsChronic cocaine usersSelf-report measuresProcedural learningSelf-reported sleepCocaine usersTotal sleep timeVigilance reaction timeSleep timeDays of abstinenceOccult insomniaElectrophysiological measuresCocaine self-administration sessionsSelf-administration sessionsImpaired vigilanceChronic insomniaSustained abstinenceSleep disturbancesAbstinenceReaction timeSlow wave activityLearningSleep latencyDays abstinenceSleepVigilance