1991
Modulation of Neonatal Neutrophil Function by Pentoxifylline
Krause P, Maderazo E, Contrino J, Eisenfeld L, Herson V, Greca N, Bannon P, Kreutzer D. Modulation of Neonatal Neutrophil Function by Pentoxifylline. Pediatric Research 1991, 29: 123-127. PMID: 2014147, DOI: 10.1203/00006450-199102000-00002.Peer-Reviewed Original ResearchConceptsPMN functionNitroblue tetrazolium reductionImpaired PMN functionsNeonatal neutrophil functionTetrazolium reductionTreatment of infectionsPolymorphonuclear leukocyte chemotaxisF-actin contentDose-dependent effectPotential clinical useCertain disease processesSimilar dose-dependent responseDose-dependent responseNeutrophil functionNewborn infantsPMN activityPMN deformabilityPMN chemotaxisDisease processPentoxifyllineLeukocyte chemotaxisMethylxanthine pentoxifyllinePhagocytic activityNeonatesClinical use
1989
Effects of Intravenous Fat Infusion on Neonatal Neutrophil and Platelet Function
Herson V, Block C, Eisenfeld L, Maderazo E, Krause P. Effects of Intravenous Fat Infusion on Neonatal Neutrophil and Platelet Function. Journal Of Parenteral And Enteral Nutrition 1989, 13: 620-622. PMID: 2515309, DOI: 10.1177/0148607189013006620.Peer-Reviewed Original ResearchMeSH KeywordsBlood PlateletsFat Emulsions, IntravenousHumansIn Vitro TechniquesInfant, NewbornNeutrophilsParenteral Nutrition, TotalConceptsPolymorphonuclear leukocytesIntralipid infusionNeonatal intensive care unitAdult polymorphonuclear leukocytesIntensive care unitIntravenous fat infusionPresence of infectionAdverse hematologic effectsNeonatal polymorphonuclear leukocytesParenteral nutritionIll neonatesNeonatal neutrophilsPMN countCare unitPlatelet countPlatelet activityHematologic effectsIntravenous fatPlatelet functionPlatelet numberUnchanged preFat infusionPlatelet aggregationInfusionIntralipid
1987
The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis
Fuenfer M, Herson V, Raye J, Woronick C, Eisenfeld L, Ingardia C, Block C, Krause P. The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis. Pediatric Research 1987, 22: 150-153. PMID: 3658539, DOI: 10.1203/00006450-198708000-00009.Peer-Reviewed Original ResearchMeSH KeywordsBacterial InfectionsBetamethasoneChemotaxis, LeukocyteFetal BloodHumansIn Vitro TechniquesInfant, NewbornNeutrophilsConceptsEffect of betamethasoneBacterial infectionsNewborn infantsPMN functionMaternal glucocorticoid administrationNeonatal PMN functionFetal lung maturationMigration of PMNRandom migrationConcentrations of betamethasonePMN random migrationSignificant clinical importanceBetamethasone administrationGlucocorticoid administrationPregnant womenLung maturationNeutrophil functionStandard doseCord bloodNeutrophil chemotaxisAntiinflammatory agentsClinical importanceImportant causeImmune systemBetamethasone
1986
Polymorphonuclear Leukocyte Adherence and Chemotaxis in Stressed and Healthy Neonates
Krause P, Herson V, Boutin-Lebowitz J, Eisenfeld L, Block C, LoBello T, Maderazo E. Polymorphonuclear Leukocyte Adherence and Chemotaxis in Stressed and Healthy Neonates. Pediatric Research 1986, 20: 296-300. PMID: 3703618, DOI: 10.1203/00006450-198604000-00004.Peer-Reviewed Original ResearchConceptsStressed neonatesHealthy neonatesPMN adherencePMN chemotaxisAcute lower respiratory illnessBacterial infectionsPolymorphonuclear neutrophil (PMN) adherenceLower respiratory illnessPolymorphonuclear leukocyte adherenceRespiratory illnessNeutrophil adherenceLeukocyte adherenceFurther impairmentNeonatesHealthy adultsImportant causeGreater riskInfectionChemotaxis assaysAdherenceAdultsIllnessChemotaxisSignificant improvementSusceptibility