2020
Borrelia burgdorferi and Borrelia miyamotoi seroprevalence in California blood donors
Brummitt SI, Kjemtrup AM, Harvey DJ, Petersen JM, Sexton C, Replogle A, Packham AE, Bloch EM, Barbour AG, Krause PJ, Green V, Smith WA. Borrelia burgdorferi and Borrelia miyamotoi seroprevalence in California blood donors. PLOS ONE 2020, 15: e0243950. PMID: 33370341, PMCID: PMC7769429, DOI: 10.1371/journal.pone.0243950.Peer-Reviewed Original ResearchConceptsLyme diseaseBlood donorsB. miyamotoiB. burgdorferiEndemic countiesWestern blotBorrelia miyamotoiB. burgdorferi antibodiesAdult blood donorsBorrelia burgdorferiIgG Western blotBlood donor seraRisk of infectionELISA test systemBurgdorferi antibodiesDonor seraC6 ELISAClinical casesEquivocal samplesHuman casesDiseaseAntibodiesI. pacificus ticksMiyamotoiBurgdorferi
2019
Seroprevalence of <em>Borrelia burgdorferi</em>, <em>B. miyamotoi</em>, and Powassan Virus in Residents Bitten by <em>Ixodes</em> Ticks, Maine, USA - Volume 25, Number 4—April 2019 - Emerging Infectious Diseases journal - CDC
Smith RP, Elias SP, Cavanaugh CE, Lubelczyk CB, Lacombe EH, Brancato J, Doyle H, Rand PW, Ebel GD, Krause PJ. Seroprevalence of Borrelia burgdorferi, B. miyamotoi, and Powassan Virus in Residents Bitten by Ixodes Ticks, Maine, USA - Volume 25, Number 4—April 2019 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2019, 25: 804-807. PMID: 30882312, PMCID: PMC6433028, DOI: 10.3201/eid2504.180202.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBorreliaBorrelia burgdorferiEncephalitis Viruses, Tick-BorneHumansIxodesMaineSeroepidemiologic StudiesTick BitesTick-Borne Diseases
2015
Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences
Diuk-Wasser MA, Vannier E, Krause PJ. Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences. Trends In Parasitology 2015, 32: 30-42. PMID: 26613664, PMCID: PMC4713283, DOI: 10.1016/j.pt.2015.09.008.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArachnid VectorsBabesia microtiBabesiosisBorrelia burgdorferiCoinfectionHumansIxodesLyme DiseaseConceptsB. microtiDisease severityGreater disease severityEnzootic cycleCoinfected individualsTick-borne pathogenClinical consequencesTherapeutic strategiesLyme diseaseBabesia microtiHost factorsCoinfectionBorrelia burgdorferiB. burgdorferiIxodes ticksMicrotiReservoir hostsSeverityHuman pathogensBurgdorferi
2013
Lyme Disease and the Heart
Krause PJ, Bockenstedt LK. Lyme Disease and the Heart. Circulation 2013, 127: e451-e454. PMID: 23429899, DOI: 10.1161/circulationaha.112.101485.Peer-Reviewed Original Research
2007
Serum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿
Hsieh YF, Liu HW, Hsu TC, Wei J, Shih CM, Krause PJ, Tsay GJ. Serum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿. MSphere 2007, 14: 1437-1441. PMID: 17881508, PMCID: PMC2168181, DOI: 10.1128/cvi.00151-07.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, BacterialAntigens, BacterialAntigens, SurfaceArthritis, RheumatoidAutoimmune DiseasesBacterial Outer Membrane ProteinsBacterial VaccinesBlotting, WesternBorrelia burgdorferiEnzyme-Linked Immunosorbent AssayFemaleHumansLipoproteinsLyme DiseaseMaleMiddle AgedRecombinant Fusion ProteinsConceptsRheumatoid arthritis patientsRheumatoid arthritisOspA antigenArthritis patientsAutoimmune diseasesSerum reactivityLyme diseaseDisease Activity ScoreCommon clinical featuresLyme disease patientsSurface protein AArthritis correlatesSynovial histologyOuter surface protein ALyme arthritisActivity scoreClinical featuresDisease patientsSerum concentrationsSimilar pathogenesisHealthy subjectsPatientsArthritisDisease severityDisease
2005
Hypersensitivity to Ticks and Lyme Disease Risk
Burke G, Wikel SK, Spielman A, Telford SR, McKay K, Krause PJ, . Hypersensitivity to Ticks and Lyme Disease Risk. Emerging Infectious Diseases 2005, 11: 36-41. PMID: 15705320, PMCID: PMC3294369, DOI: 10.3201/eid1101.040303.Peer-Reviewed Original ResearchConceptsTick biteLyme diseaseLyme disease-endemic regionsNymphal Ixodes scapularis ticksLyme disease infectionDisease-endemic regionsCutaneous hypersensitivityIxodes scapularis ticksStudy participantsDisease riskPrior exposureDiseaseBorrelia burgdorferiFrequent exposureScapularis ticksBiteItchLyme disease riskHypersensitivityVector ticksTicksPrevious yearExposureDisease infectionResidents