1987
Immune recognition of human major histocompatibility antigens: localization by a comprehensive synthetic strategy of the continuous antigenic sites in the first domain of HLA‐DR2 β chain
Ulrich R, Atassi H, Lutz P, Cresswell P, Atassi M. Immune recognition of human major histocompatibility antigens: localization by a comprehensive synthetic strategy of the continuous antigenic sites in the first domain of HLA‐DR2 β chain. European Journal Of Immunology 1987, 17: 497-502. PMID: 2436923, DOI: 10.1002/eji.1830170410.Peer-Reviewed Original ResearchConceptsAntibody-binding activityHuman major histocompatibility antigensBeta chainMajor histocompatibility antigensAntigenic sitesHistocompatibility antigensImmune recognitionChain antiserumIsolated beta chainsMost antiseraAntiserumPeptide 81Continuous antigenic sitesΒ-chainPeptidesFirst domainHLAImmunodominanceAntigenComprehensive synthetic strategy
1984
HLA-DR7-Specific monoclonal antibodies and a chimpanzee anti-DR7 serum detect different epitopes on the same molecule
Radka S, Bernard Amos D, Quackenbush L, Cresswell P. HLA-DR7-Specific monoclonal antibodies and a chimpanzee anti-DR7 serum detect different epitopes on the same molecule. Immunogenetics 1984, 19: 63-76. PMID: 6198273, DOI: 10.1007/bf00364476.Peer-Reviewed Original ResearchConceptsClass II moleculesChimpanzee antiserumSame class II moleculesDR7 specificitiesSerologic specificityMonoclonal antibodiesBinding-inhibition studiesCell linesSame serologic specificityAllogeneic epitopesNoncytotoxic antibodiesHLA-DR7IgM antibodiesSpecific monoclonal antibodiesDR moleculesDifferent epitopesAntibodiesEpitopesBeta chainCytotoxic activityHomozygous cell linesAntiserumMembrane preparationsCytotoxicitySpecificity
1978
Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response
Geier S, Cresswell P. Rabbit antiserum to human B-cell alloantigens II. Mechanism of inhibition of stimulation in the mixed lymphocyte response. Cellular Immunology 1978, 35: 392-402. PMID: 145900, DOI: 10.1016/0008-8749(78)90158-2.Peer-Reviewed Original ResearchConceptsAntibody-dependent cell-mediated cytotoxicityMixed lymphocyte responseAnti-B cell serumLymphocyte responsesDependent cell-mediated cytotoxicityInhibition of monocyteHuman B cell alloantigensADCC effector cellsCell-mediated cytotoxicityImmunoglobulin-positive cellsB-cell alloantigensRabbit antiserumEffector cellsMLR suppressionImmune eliminationStimulator cellsPositive cellsLevel of inhibitionMarked reductionCell populationsChicken antiseraAntiserumSimilar specificityMechanism of inhibitionFc region
1976
HLA antigens: rabbit antisera reacting with all A series or all B series specificities
Cresswell P, Ayres J. HLA antigens: rabbit antisera reacting with all A series or all B series specificities. European Journal Of Immunology 1976, 6: 82-88. PMID: 786698, DOI: 10.1002/eji.1830060203.Peer-Reviewed Original ResearchConceptsCytotoxicity of HLAHLA alloantiseraHLA antigensA2 substanceHuman peripheral blood lymphocytesPeripheral blood lymphocytesComplement-mediated cytotoxicityType of serumHLA-B12HLA-A2Blood lymphocytesHLA-B7Beta 2microglobulinHLAFragments of rabbitHLA lociCultured cell linesAntigenic determinantsAllelic productsRabbitsCell linesImmune precipitationRabbit antiserumAntigenAntiserum
1971
THE CYTOTOXIC EFFECT ON HUMAN LYMPHOCYTES OF RABBIT ANTISERA TO HUMAN FC (IGG)
WELSH K, CRESSWELL P, GOUJET C, SANDERSON A. THE CYTOTOXIC EFFECT ON HUMAN LYMPHOCYTES OF RABBIT ANTISERA TO HUMAN FC (IGG). Transplantation 1971, 12: 468-471. PMID: 5165966, DOI: 10.1097/00007890-197112000-00009.Peer-Reviewed Original Research