2020
Germline NLRP7 mutations: genomic imprinting and hydatidiform mole
Hui P. Germline NLRP7 mutations: genomic imprinting and hydatidiform mole. Virchows Archiv 2020, 477: 175-176. PMID: 32577811, DOI: 10.1007/s00428-020-02802-y.Peer-Reviewed Original ResearchHeterozygous/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease
Zheng XZ, Qin XY, Chen SW, Wang P, Zhan Y, Zhong PP, Buza N, Jin YL, Wu BQ, Hui P. Heterozygous/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease. Modern Pathology 2020, 33: 1979-1988. PMID: 32404958, DOI: 10.1038/s41379-020-0566-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleGenotypeHumansHydatidiform MoleHydatidiform Mole, InvasiveMiddle AgedPregnancyUterine NeoplasmsYoung AdultConceptsNon-molar gestationsGestational trophoblastic diseaseTrophoblastic diseaseHigh riskGestational trophoblastic neoplasiaProducts of conceptionPatient demographicsClinical followClinical outcomesGynecology HospitalTrophoblastic neoplasiaBeijing ObstetricsFIGO criteriaChinese patientsClinical prognosisPatient managementLarge cohortGestationMolar gestationDiseaseGenetic abnormalitiesChromosomal monosomyChromosomal aneuploidyHydatidiformUniparental disomy
2019
Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles
Buza N, McGregor SM, Barroilhet L, Zheng X, Hui P. Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles. Modern Pathology 2019, 32: 1180-1188. PMID: 30952972, DOI: 10.1038/s41379-019-0266-0.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, MissedAdultAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorChromosomes, Human, Pair 11CyclophosphamideDactinomycinEtoposideFemaleGenetic LociGenetic Predisposition to DiseaseHumansHydatidiform MoleMaleMethotrexatePhenotypePregnancyTreatment OutcomeTyrosine 3-MonooxygenaseUniparental DisomyUterine NeoplasmsVincristineConceptsPaternal uniparental isodisomyAbnormal trophoblastic proliferationCases of gestationUneventful clinical courseAggressive clinical behaviorUniparental isodisomyTyrosine hydroxylase locusMultiagent chemotherapyClinical courseFirst trimesterClinical complicationsImmunohistochemical featuresClinical behaviorMissed abortionAbnormal gestationsTyrosine hydroxylasePatientsTrophoblastic proliferationVillous cytotrophoblastsStromal cellsPhenotypical presentationChorionic villiGenetic conditionsP57 expressionGestation
2017
Hydatidiform Moles: Genetic Basis and Precision Diagnosis
Hui P, Buza N, Murphy KM, Ronnett BM. Hydatidiform Moles: Genetic Basis and Precision Diagnosis. Annual Review Of Pathology Mechanisms Of Disease 2017, 12: 449-485. PMID: 28135560, DOI: 10.1146/annurev-pathol-052016-100237.Peer-Reviewed Original Research
2015
[Ancillary techniques in refining the diagnosis of hydatidiform mole].
Zheng X, Wu B, Buza N, Hui P. [Ancillary techniques in refining the diagnosis of hydatidiform mole]. 中华病理学杂志 2015, 44: 15-20. PMID: 25765025.Peer-Reviewed Original Research
2014
Egg Donor Pregnancy
Buza N, Hui P. Egg Donor Pregnancy. International Journal Of Gynecological Pathology 2014, 33: 507-510. PMID: 25083967, DOI: 10.1097/pgp.0b013e3182a1028b.Peer-Reviewed Original ResearchMeSH KeywordsAdultAllelesFemaleFertilization in VitroGenotypeHumansHydatidiform MoleMicrosatellite RepeatsOocyte DonationPregnancyUterine NeoplasmsConceptsDonor pregnanciesMedical recordsClinical gestational ageFirst case reportPatients' medical recordsPositive nuclear stainingNormal staining patternVillous stromal cellsMaternal decidual tissuesDNA genotypingChorionic villous tissueGestational ageUnderwent dilationCase reportUterine contentsVillous tissueMorphologic featuresStromal cellsPregnancyStaining patternComplete hydatidiformPartial hydatidiformChorionic villiNuclear stainingMicroscopic evaluationSTR DNA genotyping of hydatidiform moles in South China.
Zheng XZ, Hui P, Chang B, Gao ZB, Li Y, Wu BQ, Zhang B. STR DNA genotyping of hydatidiform moles in South China. International Journal Of Clinical And Experimental Pathology 2014, 7: 4704-19. PMID: 25197342, PMCID: PMC4152032.Peer-Reviewed Original Research
2013
Partial Hydatidiform Mole
Buza N, Hui P. Partial Hydatidiform Mole. International Journal Of Gynecological Pathology 2013, 32: 307-315. PMID: 23518914, DOI: 10.1097/pgp.0b013e3182626011.Peer-Reviewed Original ResearchConceptsVillous sizeVillous hydropsMorphologic featuresHigh positive predictive valueCases of PHMSignificant histologic overlapPositive predictive valuePopulations of villusPartial Hydatidiform MoleCistern formationRoutine workupGynecologic pathologistsVillus sizeDefinitive diagnosisHistologic diagnosisHistologic findingsAvailable hematoxylinHistologic overlapDNA genotypingHistologic parametersEosin slidesPredictive valueDiagnostic significanceChromosomal trisomiesTrophoblastic hyperplasia
2012
[Genetic basis of molar pregnancy].
Hui P, Liu Y. [Genetic basis of molar pregnancy]. 中华病理学杂志 2012, 41: 721-4. PMID: 23302329, DOI: 10.3760/cma.j.issn.0529-5807.2012.11.001.Peer-Reviewed Original Research
2010
Molecular diagnosis of gestational trophoblastic disease
Hui P. Molecular diagnosis of gestational trophoblastic disease. Expert Review Of Molecular Diagnostics 2010, 10: 1023-1034. PMID: 21080819, DOI: 10.1586/erm.10.93.Peer-Reviewed Original Research
2008
Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis
Bifulco C, Johnson C, Hao L, Kermalli H, Bell S, Hui P. Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis. The American Journal Of Surgical Pathology 2008, 32: 445-451. PMID: 18300805, DOI: 10.1097/pas.0b013e3181520034.Peer-Reviewed Original ResearchConceptsMolar pregnancyMaternal endometrial tissuesDaily clinical practiceDNA ploidy analysisDNA genotypingCases of HMUnstained paraffin sectionsHistologic featuresEndometrial tissueMorphologic mimicsClinical practiceMolar gestationHydatidiform MoleParaffin sectionsChorionic villiDiagnosisRoutine diagnosisPregnancyPloidy analysisGenotypic analysisGenotypingPaternal originPCR amplification systemGestationCases