2021
Progression of Cystadenoma to Mucinous Borderline Ovarian Tumor in Young Females: Case Series and Literature Review
Beroukhim G, Ozgediz D, Cohen PJ, Hui P, Morotti R, Schwartz PE, Yang-Hartwich, Vash-Margita A. Progression of Cystadenoma to Mucinous Borderline Ovarian Tumor in Young Females: Case Series and Literature Review. Journal Of Pediatric And Adolescent Gynecology 2021, 35: 359-367. PMID: 34843973, DOI: 10.1016/j.jpag.2021.11.003.Peer-Reviewed Original ResearchConceptsMucinous borderline ovarian tumorsBorderline ovarian tumorsOvarian tumorsYale-New Haven HospitalRetrospective chart reviewBenign ovarian tumorsBenign ovarian lesionsRate of recurrenceNew Haven HospitalAbdominal painPreoperative characteristicsChart reviewDisease recurrenceRecurrent cystsCase seriesChief complaintClinical presentationClinicopathologic featuresFemale patientsMucinous cystadenomaOvarian cystsOvarian lesionsTumor stageAdolescent patientsSubsequent surveillance
2020
Lack of genetic homozygosity in prepubertal teratomas: divergent pathogenesis distinct from that of teratomas in adolescents
Snir OL, DeJoseph M, Wu X, Rottmann D, Wong S, Buza N, Hui P. Lack of genetic homozygosity in prepubertal teratomas: divergent pathogenesis distinct from that of teratomas in adolescents. Laboratory Investigation 2020, 100: 1447-1454. PMID: 32694569, DOI: 10.1038/s41374-020-0468-6.Peer-Reviewed Original ResearchConceptsOvarian teratomaPatient ageImmature teratomaTesticular teratomaMature teratomaSacrococcygeal teratomaMixed germ cell tumorGerm cell tumorsMature ovarian teratomaChildren 18 yearsDivergent pathogenesisGenetic zygosityPrepubertal teratomasCell tumorsGonadal teratomaTeratomaGenetic homozygosityNormal tissuesPatientsGerm cell developmentSacrococcygealAgeCell developmentDepartmental archivesGerm cells
2019
Prognostic markers for immunodeficiency-associated primary central nervous system lymphoma
Kaulen LD, Galluzzo D, Hui P, Barbiero F, Karschnia P, Huttner A, Fulbright R, Baehring JM. Prognostic markers for immunodeficiency-associated primary central nervous system lymphoma. Journal Of Neuro-Oncology 2019, 144: 107-115. PMID: 31190317, DOI: 10.1007/s11060-019-03208-w.Peer-Reviewed Original ResearchConceptsPrimary central nervous system lymphomaDiffusion-weighted imaging patternsMagnetic resonance imagingCentral nervous system lymphomaNervous system lymphomaSystem lymphomaPeripheral enhancementDWI patternsPCNSL casesImaging featuresPrognostic markerHuman immunodeficiency virus (HIV) infectionKaplan-Meier survival analysisDiffuse large B-cell lymphomaYale-New Haven HospitalLarge B-cell lymphomaMedian overall survivalImmunodeficiency virus infectionPredictors of survivalSolid organ transplantationImmunoglobulin heavy chain gene rearrangementPeripheral contrast enhancementLog-rank testMajor risk factorHeavy chain gene rearrangement
2017
Low-Grade Astrocytoma within a Mature Cystic Teratoma in an Adolescent Patient
Yoder N, Marks A, Hui P, Litkouhi B, Cron J. Low-Grade Astrocytoma within a Mature Cystic Teratoma in an Adolescent Patient. Journal Of Pediatric And Adolescent Gynecology 2017, 31: 325-327. PMID: 29107097, DOI: 10.1016/j.jpag.2017.10.005.Peer-Reviewed Original ResearchConceptsMature cystic teratomaCystic teratomaLow-grade astrocytomasAdolescent patientsMalignant transformationAsymptomatic ovarian cystsCommon ovarian neoplasmsLarger tumor sizeGynecologic tractSubsequent cystectomyPostmenopausal statusFinal pathologyOvarian neoplasmsOvarian cystsTumor sizeRisk factorsGlial tissueGrade astrocytomasAntigen 125Mouse modelSolid tumorsPatientsAstrocytomasTeratomaTrisomy 20Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma
Hardee S, Prasad ML, Hui P, Dinauer CA, Morotti RA. Pathologic Characteristics, Natural History, and Prognostic Implications of BRAFV600E Mutation in Pediatric Papillary Thyroid Carcinoma. Pediatric And Developmental Pathology 2017, 20: 206-212. PMID: 28521635, DOI: 10.1177/1093526616689628.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerPediatric papillary thyroid cancerPrognostic implicationsPediatric papillary thyroid carcinomaNegative casesBRAF-negative casesBRAF-negative patientsBRAF-positive casesTertiary medical centerAggressive clinical coursePapillary thyroid carcinomaSurgical pathology diagnosisCommon genetic aberrationsNegative patientsAggressive courseClinical coursePathologic characteristicsCase seriesClinical outcomesRetrospective reviewAggressive featuresPediatric casesRecurrence rateRetrospective studySingle institution
2015
Craniopharyngioma arising in a Rathke's cleft cyst: case report.
Alomari AK, Kelley BJ, Damisah E, Marks A, Hui P, DiLuna M, Vortmeyer A. Craniopharyngioma arising in a Rathke's cleft cyst: case report. Journal Of Neurosurgery Pediatrics 2015, 15: 250-4. PMID: 25555112, DOI: 10.3171/2014.11.peds14370.Peer-Reviewed Original ResearchConceptsRathke's cleft cystCleft cystDecreased visual acuityFocal squamous metaplasiaHistological findingsSquamous metaplasiaVisual acuityCase reportRim enhancementSellar lesionsSerial MRIIntracranial tumorsKi-67Histological examinationBRAF mutationsYears durationSellar regionLesion typeLesionsResidual enhancementCraniopharyngiomaMolecular classificationEctodermal lesionsPatientsCysts
2012
Papillary thyroid carcinomas with and without BRAF V600E mutations are morphologically distinct
Finkelstein A, Levy GH, Hui P, Prasad A, Virk R, Chhieng DC, Carling T, Roman SA, Sosa JA, Udelsman R, Theoharis CG, Prasad ML. Papillary thyroid carcinomas with and without BRAF V600E mutations are morphologically distinct. Histopathology 2012, 60: 1052-1059. PMID: 22335197, DOI: 10.1111/j.1365-2559.2011.04149.x.Peer-Reviewed Original Research
2011
Reflex BRAF Testing in Thyroid Fine-Needle Aspiration Biopsy with Equivocal and Positive Interpretation: A Prospective Study
Adeniran AJ, Theoharis C, Hui P, Prasad ML, Hammers L, Carling T, Udelsman R, Chhieng DC. Reflex BRAF Testing in Thyroid Fine-Needle Aspiration Biopsy with Equivocal and Positive Interpretation: A Prospective Study. Thyroid 2011, 21: 717-723. PMID: 21568726, DOI: 10.1089/thy.2011.0021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBiomarkers, TumorBiopsy, Fine-NeedleCarcinomaCarcinoma, PapillaryChildDNA Mutational AnalysisFemaleHumansMaleMiddle AgedPoint MutationPolymorphism, Single-Stranded ConformationalProspective StudiesProto-Oncogene Proteins B-rafThyroid Cancer, PapillaryThyroid GlandThyroid Neoplasms